Progression in Near-Infrared Fluorescence Imaging Technology for Lung Cancer Management
Lung cancer is a major threat to human health and a leading cause of death. Accurate localization of tumors in vivo is crucial for subsequent treatment. In recent years, fluorescent imaging technology has become a focal point in tumor diagnosis and treatment due to its high sensitivity, strong selec...
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| Format: | Article |
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MDPI AG
2024-10-01
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| Series: | Biosensors |
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| Online Access: | https://www.mdpi.com/2079-6374/14/10/501 |
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| author | Xinglong Chen Yuning Li Jialin Su Lemeng Zhang Hongwen Liu |
| author_facet | Xinglong Chen Yuning Li Jialin Su Lemeng Zhang Hongwen Liu |
| author_sort | Xinglong Chen |
| collection | DOAJ |
| description | Lung cancer is a major threat to human health and a leading cause of death. Accurate localization of tumors in vivo is crucial for subsequent treatment. In recent years, fluorescent imaging technology has become a focal point in tumor diagnosis and treatment due to its high sensitivity, strong selectivity, non-invasiveness, and multifunctionality. Molecular probes-based fluorescent imaging not only enables real-time in vivo imaging through fluorescence signals but also integrates therapeutic functions, drug screening, and efficacy monitoring to facilitate comprehensive diagnosis and treatment. Among them, near-infrared (NIR) fluorescence imaging is particularly prominent due to its improved in vivo imaging effect. This trend toward multifunctionality is a significant aspect of the future advancement of fluorescent imaging technology. In the past years, great progress has been made in the field of NIR fluorescence imaging for lung cancer management, as well as the emergence of new problems and challenges. This paper generally summarizes the application of NIR fluorescence imaging technology in these areas in the past five years, including the design, detection principles, and clinical applications, with the aim of advancing more efficient NIR fluorescence imaging technologies to enhance the accuracy of tumor diagnosis and treatment. |
| format | Article |
| id | doaj-art-442c94796309488ca09db4f5ff0dce30 |
| institution | OA Journals |
| issn | 2079-6374 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj-art-442c94796309488ca09db4f5ff0dce302025-08-20T02:11:09ZengMDPI AGBiosensors2079-63742024-10-01141050110.3390/bios14100501Progression in Near-Infrared Fluorescence Imaging Technology for Lung Cancer ManagementXinglong Chen0Yuning Li1Jialin Su2Lemeng Zhang3Hongwen Liu4Thoracic Medicine Department 1, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, Changsha 410013, ChinaThoracic Medicine Department 1, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, Changsha 410013, ChinaThoracic Medicine Department 1, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, Changsha 410013, ChinaThoracic Medicine Department 1, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, Changsha 410013, ChinaCollege of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, ChinaLung cancer is a major threat to human health and a leading cause of death. Accurate localization of tumors in vivo is crucial for subsequent treatment. In recent years, fluorescent imaging technology has become a focal point in tumor diagnosis and treatment due to its high sensitivity, strong selectivity, non-invasiveness, and multifunctionality. Molecular probes-based fluorescent imaging not only enables real-time in vivo imaging through fluorescence signals but also integrates therapeutic functions, drug screening, and efficacy monitoring to facilitate comprehensive diagnosis and treatment. Among them, near-infrared (NIR) fluorescence imaging is particularly prominent due to its improved in vivo imaging effect. This trend toward multifunctionality is a significant aspect of the future advancement of fluorescent imaging technology. In the past years, great progress has been made in the field of NIR fluorescence imaging for lung cancer management, as well as the emergence of new problems and challenges. This paper generally summarizes the application of NIR fluorescence imaging technology in these areas in the past five years, including the design, detection principles, and clinical applications, with the aim of advancing more efficient NIR fluorescence imaging technologies to enhance the accuracy of tumor diagnosis and treatment.https://www.mdpi.com/2079-6374/14/10/501lung cancerdiagnosistreatmentnear-infrared fluorescencein vivo imaging |
| spellingShingle | Xinglong Chen Yuning Li Jialin Su Lemeng Zhang Hongwen Liu Progression in Near-Infrared Fluorescence Imaging Technology for Lung Cancer Management Biosensors lung cancer diagnosis treatment near-infrared fluorescence in vivo imaging |
| title | Progression in Near-Infrared Fluorescence Imaging Technology for Lung Cancer Management |
| title_full | Progression in Near-Infrared Fluorescence Imaging Technology for Lung Cancer Management |
| title_fullStr | Progression in Near-Infrared Fluorescence Imaging Technology for Lung Cancer Management |
| title_full_unstemmed | Progression in Near-Infrared Fluorescence Imaging Technology for Lung Cancer Management |
| title_short | Progression in Near-Infrared Fluorescence Imaging Technology for Lung Cancer Management |
| title_sort | progression in near infrared fluorescence imaging technology for lung cancer management |
| topic | lung cancer diagnosis treatment near-infrared fluorescence in vivo imaging |
| url | https://www.mdpi.com/2079-6374/14/10/501 |
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