Shi Wei Ru Xiang pill alleviates acute gouty arthritis through suppressing NLRP3 inflammasome activation

Shi Wei Ru Xiang pill alleviates acute gouty arthritis through suppressing NLRP3 inflammasome activation

IntroductionShi Wei Ru Xiang pill (SWR) is commonly utilized in Tibetan medicine as a therapeutic intervention for “Huang-shui disease” and has been clinically validated as an effective treatment for acute gouty arthritis (AGA). Nevertheless, the underlying mechanisms of action and the active compon...

Full description

Saved in:

Bibliographic Details
Main Authors:	Na Wang, Puchen Zhao, Qin Yin, Lizi Li, Haiqi Xu, Can Yang, Yanbei Tu, Yanfang Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Pharmacology
Subjects:	Shi Wei Ru Xiang pill NLRP3 inflammasome acute gouty arthritis Tibetan medicine monosodium urate
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1595578/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Gouty arthritis: An approach for general practice
by: M. Tikly, et al.
Published: (2013-08-01)

Total Glucosides of Paeony (TGP) Inhibits Macrophages Infiltration and NLRP3-Mediated Inflammatory Response in Acute Gouty Arthritis Mice
by: Liu J, et al.
Published: (2025-07-01)

Suppressing chondrocyte cuproptosis by syringaresinol-4-O-β-d-glucoside alleviates gouty arthritis
by: Shaotian Fu, et al.
Published: (2025-05-01)

Determination of rutin, hyperoside, quercetin in Xiang lotus by HPLC
by: ZHONG Feifei, et al.
Published: (2023-10-01)

The role of renal dual-energy computed tomography in exploring the gouty kidney: the RENODECT study
by: Tristan Pascart, et al.
Published: (2025-12-01)

The evolution and transformation of Wei-Jin metaphysics
by: ChunXia Li
Published: (2025-04-01)

Effects of soybean isoflavones on reproductive organ development and biochemical indices of male Xiang pigs
by: FAN Jue-xin, et al.
Published: (2012-07-01)

Professor Wei-bin GAO's experience in treatment of voiding dysfunction with electroacupuncture
by: Shao-peng LIU, et al.
Published: (2024-10-01)

Pharmacokinetics and Ex Vivo Activity of 7-Methylxanthine, an Inhibitor of Monosodium Urate Crystallization
by: Miguel D. Ferrer, et al.
Published: (2025-06-01)

Gouty tophus in the vocal fold: A rare case report
by: Zijian He, et al.
Published: (2025-12-01)

Identification of the putative regulatory regions and candidate genes associated with backfat thickness and intramuscular fat content traits in Xiang pigs
by: Xia Chen, et al.
Published: (2025-08-01)

Yuan：Research on the Fen-wei rift valley
by: Rui Feng
Published: (2025-01-01)

The Range and Evolution Model of the Xiang-E Submarine Uplifts at the Ordovician–Silurian Transition: Evidence from Black Shale Graptolites
by: Zhi Zhou, et al.
Published: (2025-04-01)

Diagnosis and Treatment of Lung Cancer Complicated with Sepsis from Perspective of "Yang Wei Yin Xian" Theory
by: Qinghua LIU, et al.
Published: (2025-05-01)

Multivariate analyses to evaluate the contamination, ecological risk, and source apportionment of heavy metals in the surface sediments of Xiang-Shan wetland, Taiwan
by: Ahmed Salah-Tantawy, et al.
Published: (2025-04-01)

The Image Transformation and Literary Writing of Buddhist Temples in Northern Wei Luoyang
by: Yan Gong
Published: (2025-02-01)

Self-Transcendence and Its Discontents: Criticisms and Defences of the <i>Zhuangzi</i> in Wei-Jin Thought and Their Modern Significance
by: Benjamin Coles
Published: (2025-04-01)

Search for double β-decays of 96Ru and 104Ru with high purity Ge γ-spectrometry
by: P. Belli, et al.
Published: (2010-12-01)

The Geographical Dispersion of the Shi‘ah In the Ilkhanid Iran
by: Hoseyn-e Ebrahimi
Published: (2006-08-01)

Problem of Ecology of Soul in Works by V. Astafyev and Zhang Wei
by: S. V. Burdina, et al.
Published: (2019-03-01)

MELASMA SHOW UP IN CONTRACEPTIVE PILLS ACCEPTORS
by: Cahya Novenita Azzahra, et al.
Published: (2021-01-01)

Moxibustion inhibits inflammation in monosodium urate crystal-induced gouty arthritis model rats through metabolomic regulation
by: Yufeng Xie, et al.
Published: (2025-03-01)

GDF-15 Levels in Gouty Arthritis and Correlations with Decreasing Renal Function: A Clinical Study
by: Osman Cure, et al.
Published: (2025-07-01)

Phellodendrine chloride alleviates gouty arthritis through IL-6/STAT3 signaling pathway
by: Yu-yao Qin, et al.
Published: (2025-07-01)

Case report: A case of tibial tuberous osteochondroma complicated with gouty calculus
by: Qiang Zhang, et al.
Published: (2025-05-01)

ULTRASONOGRAPHIC CHANGES IN THE HYALINE CARTILAGE: EVALUATION OF SENSITIVITY AND SPECIFICITY IN EARLY GOUTY ARTHRITIS
by: A. V. Petrov, et al.
Published: (2017-07-01)

Monoarticular Crystal Arthropathy of the Knee: Tophaceous Gout
by: Ravikanth Reddy
Published: (2021-10-01)

The Role of Urate in Calcium Stone Formation
by: Erika Critell, et al.
Published: (2024-11-01)

Adjacent segment disease induced by spinal tophus: a case report
by: Chenglong Wang, et al.
Published: (2025-05-01)

Elucidating the Differential Mechanisms of Jingui Shenqi Pill and Mingmu Dihuang Pill in the Treatment of Diabetic Nephropathy Based on Yin-Yang Theory
by: Bi S, et al.
Published: (2025-04-01)

Acupuncture as an Adjunctive Therapy to Etoricoxib for Patients with Acute Gouty Arthritis: Protocol for a Multicenter Randomized Controlled Trial
by: Wang YR, et al.
Published: (2025-06-01)

Rapid Synthesis of Carbon‐Supported Ru‐RuO₂ Heterostructures for Efficient Electrochemical Water Splitting
by: Dingjie Pan, et al.
Published: (2025-03-01)

Assessing core body temperature in a cool marathon using two pill ingestion strategies
by: Grivas Gerasimos V., et al.
Published: (2024-08-01)

Shi'ah Maghtal-Writing (From the beginning to the end 5th century A.H lunar)
by: Mohammad Javad Yavari
Published: (2007-12-01)

The causal relationship between gut microbiota and gouty nephropathy based on two-sample bidirectional Mendelian randomization
by: Xiao Mei-di, et al.
Published: (2025-07-01)

Confining Flat Ru Islands into TiO2 Lattice with the Coexisting Ru–O–Ti and Ru–Ti Bonds for Ultra‐Stable Hydrogen Evolution at Amperometric Current Density and Hydrogen Oxidation at High Potential
by: Luyun Chen, et al.
Published: (2024-12-01)

Variation sur une coupure : « short of » et « shy of », entre division et discernement
by: Philippe Muller
Published: (2015-06-01)

Ḥusniyyāt or Ḥasen Shi‘r as an Independent Genre in Classical Turkish Poetry
by: Bünyamin Taş
Published: (2024-12-01)

A Rare Case Report of an Adult With Intraspinal Gouty Stones and Concurrent Knee Joint Involvement
by: Bo Cao, et al.
Published: (2025-07-01)

Corrigendum: Investigating the mechanisms of resveratrol in the treatment of gouty arthritis through the integration of network pharmacology and metabolics
by: Xiaomin Xu, et al.
Published: (2025-02-01)