Dengue fever outbreak among children in Karachi ecperience at a tertiary care children hospital

Objective: To study the natural history of disease in terms of clinical presentation and outcome in hospitalized children with confirmed dengue cases. Methods: A case series study was conducted at National Institute of Child Health (NICH), Karachi from September through November 2006. Children pr...

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Main Authors: Abdul Ghaffar Nagi, Raffat Murad, Mukhtiar Baig
Format: Article
Language:English
Published: Bahria Univerisy Health Sciences, Campus Karachi 2011-12-01
Series:Journal of Bahria University Medical and Dental College
Subjects:
Online Access:https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/19
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author Abdul Ghaffar Nagi
Raffat Murad
Mukhtiar Baig
author_facet Abdul Ghaffar Nagi
Raffat Murad
Mukhtiar Baig
author_sort Abdul Ghaffar Nagi
collection DOAJ
description Objective: To study the natural history of disease in terms of clinical presentation and outcome in hospitalized children with confirmed dengue cases. Methods: A case series study was conducted at National Institute of Child Health (NICH), Karachi from September through November 2006. Children presented with fever and presence of at least 2 clinical manifestations of suspected dengue infection according to WHO criteria were included in study. Patients were followed regarding clinical presentation, investigations, management and outcome. Results: A total of 152 children admitted with suspicion of having dengue fever were evaluated in the study. Dengue fever antibody IgM tested on all suspected patients along with CBC, PT/aPTT, Blood C/S, Serum protein and chest X- ray. Dengue fever IgM was positive in 111 patients. A significant majority of dengue patients belonged to peri urban slums. Common presenting symptom among dengue patients was fever (100%), rash (71.17%), vomiting (52.25%), hemorrhagic manifestation (36.03%) and fits (5.40%). Among 111 dengue positive cases 65 (58.58%) were Dengue Fever (DF) cases, 40 (36.03%) were Dengue Hemorrhagic Fever (DHF) and 6 (5.4%) were cases of Dengue Shock Syndrome (DSS). Three patients expired during their stay in hospital. Conclusion: A high percentage of dengue positive cases among suspected patients and a significant proportion of dengue hemorrhagic fever and dengue shock syndrome cases demands careful investigation and management.
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spelling doaj-art-4428513553484c5e90ebbf69a5efa9052025-08-20T03:13:14ZengBahria Univerisy Health Sciences, Campus KarachiJournal of Bahria University Medical and Dental College2220-75622617-94822011-12-0112Dengue fever outbreak among children in Karachi ecperience at a tertiary care children hospitalAbdul Ghaffar NagiRaffat MuradMukhtiar Baig Objective: To study the natural history of disease in terms of clinical presentation and outcome in hospitalized children with confirmed dengue cases. Methods: A case series study was conducted at National Institute of Child Health (NICH), Karachi from September through November 2006. Children presented with fever and presence of at least 2 clinical manifestations of suspected dengue infection according to WHO criteria were included in study. Patients were followed regarding clinical presentation, investigations, management and outcome. Results: A total of 152 children admitted with suspicion of having dengue fever were evaluated in the study. Dengue fever antibody IgM tested on all suspected patients along with CBC, PT/aPTT, Blood C/S, Serum protein and chest X- ray. Dengue fever IgM was positive in 111 patients. A significant majority of dengue patients belonged to peri urban slums. Common presenting symptom among dengue patients was fever (100%), rash (71.17%), vomiting (52.25%), hemorrhagic manifestation (36.03%) and fits (5.40%). Among 111 dengue positive cases 65 (58.58%) were Dengue Fever (DF) cases, 40 (36.03%) were Dengue Hemorrhagic Fever (DHF) and 6 (5.4%) were cases of Dengue Shock Syndrome (DSS). Three patients expired during their stay in hospital. Conclusion: A high percentage of dengue positive cases among suspected patients and a significant proportion of dengue hemorrhagic fever and dengue shock syndrome cases demands careful investigation and management. https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/19Dengue Fever, Dengue Hemorrhagic Fever, Dengue Shock Syndrome
spellingShingle Abdul Ghaffar Nagi
Raffat Murad
Mukhtiar Baig
Dengue fever outbreak among children in Karachi ecperience at a tertiary care children hospital
Journal of Bahria University Medical and Dental College
Dengue Fever, Dengue Hemorrhagic Fever, Dengue Shock Syndrome
title Dengue fever outbreak among children in Karachi ecperience at a tertiary care children hospital
title_full Dengue fever outbreak among children in Karachi ecperience at a tertiary care children hospital
title_fullStr Dengue fever outbreak among children in Karachi ecperience at a tertiary care children hospital
title_full_unstemmed Dengue fever outbreak among children in Karachi ecperience at a tertiary care children hospital
title_short Dengue fever outbreak among children in Karachi ecperience at a tertiary care children hospital
title_sort dengue fever outbreak among children in karachi ecperience at a tertiary care children hospital
topic Dengue Fever, Dengue Hemorrhagic Fever, Dengue Shock Syndrome
url https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/19
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AT raffatmurad denguefeveroutbreakamongchildreninkarachiecperienceatatertiarycarechildrenhospital
AT mukhtiarbaig denguefeveroutbreakamongchildreninkarachiecperienceatatertiarycarechildrenhospital