Increased NHC Cells in the Peritoneal Cavity of Plasmacytoma Susceptible BALB/c Mouse
BALB/c strain mice are unique in that they develop murine plasmacytoma (MPC) as a consequence of the inflammation induced by pristane oil injection in the peritoneal cavity. In this work the Treg, Th17, B1, B2, and NHC lymphocyte populations from the peritoneal environment of BALB/c, the susceptible...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2015/313140 |
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| author | Berenice Sánchez-González Francisco Javier García-Vázquez José Eduardo Farfán-Morales Luis Antonio Jiménez-Zamudio |
| author_facet | Berenice Sánchez-González Francisco Javier García-Vázquez José Eduardo Farfán-Morales Luis Antonio Jiménez-Zamudio |
| author_sort | Berenice Sánchez-González |
| collection | DOAJ |
| description | BALB/c strain mice are unique in that they develop murine plasmacytoma (MPC) as a consequence of the inflammation induced by pristane oil injection in the peritoneal cavity. In this work the Treg, Th17, B1, B2, and NHC lymphocyte populations from the peritoneal environment of BALB/c, the susceptible strain, and C57BL/6 mice, which do not develop MPC after oil treatment, were studied. Both oil-treated strains showed decreased levels of Th17 lymphocytes, no significant variation in Treg lymphocytes, and a drastic decrease of all B lymphocyte populations. However, only oil-induced BALB/c showed increased levels of natural helper cells (NHC) which could be important in the myeloma induction. |
| format | Article |
| id | doaj-art-44138ee659c04ea88da6db7fac5d0199 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-44138ee659c04ea88da6db7fac5d01992025-02-03T01:10:56ZengWileyMediators of Inflammation0962-93511466-18612015-01-01201510.1155/2015/313140313140Increased NHC Cells in the Peritoneal Cavity of Plasmacytoma Susceptible BALB/c MouseBerenice Sánchez-González0Francisco Javier García-Vázquez1José Eduardo Farfán-Morales2Luis Antonio Jiménez-Zamudio3Departamento de Inmunología, Laboratorio de Inmunología Clínica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, 11340 Mexico, DF, MexicoDepartamento de Anatomía Patológica, Laboratorio de Patología Molecular, Instituto Nacional de Pediatría, 04530 Mexico, DF, MexicoDepartamento de Anatomía Patológica, Laboratorio de Patología Molecular, Instituto Nacional de Pediatría, 04530 Mexico, DF, MexicoDepartamento de Inmunología, Laboratorio de Inmunología Clínica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, 11340 Mexico, DF, MexicoBALB/c strain mice are unique in that they develop murine plasmacytoma (MPC) as a consequence of the inflammation induced by pristane oil injection in the peritoneal cavity. In this work the Treg, Th17, B1, B2, and NHC lymphocyte populations from the peritoneal environment of BALB/c, the susceptible strain, and C57BL/6 mice, which do not develop MPC after oil treatment, were studied. Both oil-treated strains showed decreased levels of Th17 lymphocytes, no significant variation in Treg lymphocytes, and a drastic decrease of all B lymphocyte populations. However, only oil-induced BALB/c showed increased levels of natural helper cells (NHC) which could be important in the myeloma induction.http://dx.doi.org/10.1155/2015/313140 |
| spellingShingle | Berenice Sánchez-González Francisco Javier García-Vázquez José Eduardo Farfán-Morales Luis Antonio Jiménez-Zamudio Increased NHC Cells in the Peritoneal Cavity of Plasmacytoma Susceptible BALB/c Mouse Mediators of Inflammation |
| title | Increased NHC Cells in the Peritoneal Cavity of Plasmacytoma Susceptible BALB/c Mouse |
| title_full | Increased NHC Cells in the Peritoneal Cavity of Plasmacytoma Susceptible BALB/c Mouse |
| title_fullStr | Increased NHC Cells in the Peritoneal Cavity of Plasmacytoma Susceptible BALB/c Mouse |
| title_full_unstemmed | Increased NHC Cells in the Peritoneal Cavity of Plasmacytoma Susceptible BALB/c Mouse |
| title_short | Increased NHC Cells in the Peritoneal Cavity of Plasmacytoma Susceptible BALB/c Mouse |
| title_sort | increased nhc cells in the peritoneal cavity of plasmacytoma susceptible balb c mouse |
| url | http://dx.doi.org/10.1155/2015/313140 |
| work_keys_str_mv | AT berenicesanchezgonzalez increasednhccellsintheperitonealcavityofplasmacytomasusceptiblebalbcmouse AT franciscojaviergarciavazquez increasednhccellsintheperitonealcavityofplasmacytomasusceptiblebalbcmouse AT joseeduardofarfanmorales increasednhccellsintheperitonealcavityofplasmacytomasusceptiblebalbcmouse AT luisantoniojimenezzamudio increasednhccellsintheperitonealcavityofplasmacytomasusceptiblebalbcmouse |