Role of sclerostin in mastocytosis bone disease

Role of sclerostin in mastocytosis bone disease

Abstract Mastocytosis is a heterogeneous group of disorders, characterized by accumulation of clonal mast cells which can infiltrate several organs, most often spine (70%). The pathogenesis of mastocytosis bone disease is poorly understood. The main aim of the study was to investigate whether neopla...

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Main Authors: Aneta Szudy-Szczyrek, Radosław Mlak, Dominika Pigoń-Zając, Witold Krupski, Marcin Mazurek, Aleksandra Tomczak, Karolina Chromik, Aleksandra Górska, Paweł Koźlik, Adrian Juda, Anna Kokoć, Maciej Dubaj, Tomasz Sacha, Marek Niedoszytko, Grzegorz Helbig, Michał Szczyrek, Justyna Szumiło, Teresa Małecka-Massalska, Marek Hus
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Bone remodeling
Bones
Mastocytosis
Osteolysis
Osteosclerosis
Sclerostin
Online Access:https://doi.org/10.1038/s41598-024-83851-0
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