3D versus 2D Systematic Transrectal Ultrasound-Guided Prostate Biopsy: Higher Cancer Detection Rate in Clinical Practice
Objectives. To compare prostate cancer detection rates of extended 2D versus 3D biopsies and to further assess the clinical impact of this method in day-to-day practice. Methods. We analyzed the data of a cohort of 220 consecutive patients with no prior history of prostate cancer who underwent an in...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Prostate Cancer |
| Online Access: | http://dx.doi.org/10.1155/2013/783243 |
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| author | Alexandre Peltier Fouad Aoun Fouad El-Khoury Eric Hawaux Ksenija Limani Krishna Narahari Nicolas Sirtaine Roland van Velthoven |
| author_facet | Alexandre Peltier Fouad Aoun Fouad El-Khoury Eric Hawaux Ksenija Limani Krishna Narahari Nicolas Sirtaine Roland van Velthoven |
| author_sort | Alexandre Peltier |
| collection | DOAJ |
| description | Objectives. To compare prostate cancer detection rates of extended 2D versus 3D biopsies and to further assess the clinical impact of this method in day-to-day practice. Methods. We analyzed the data of a cohort of 220 consecutive patients with no prior history of prostate cancer who underwent an initial prostate biopsy in daily practice due to an abnormal PSA and/or DRE using, respectively, the classical 2D and the new 3D systems. All the biopsies were done by a single experienced operator using the same standardized protocol. Results. There was no significant difference in terms of age, total PSA, or prostate volume between the two groups. However, cancer detection rate was significantly higher using the 3D versus the 2D system, 50% versus 34% (P<0.05). There was no statistically significant difference while comparing the 2 groups in term of nonsignificant cancer detection. Conclusion. There is reasonable evidence demonstrating the superiority of the 3D-guided biopsies in detecting prostate cancers that would have been missed using the 2D extended protocol. |
| format | Article |
| id | doaj-art-440c71bb4763413e8bfc153261149885 |
| institution | Kabale University |
| issn | 2090-3111 2090-312X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Prostate Cancer |
| spelling | doaj-art-440c71bb4763413e8bfc1532611498852025-02-03T05:58:42ZengWileyProstate Cancer2090-31112090-312X2013-01-01201310.1155/2013/7832437832433D versus 2D Systematic Transrectal Ultrasound-Guided Prostate Biopsy: Higher Cancer Detection Rate in Clinical PracticeAlexandre Peltier0Fouad Aoun1Fouad El-Khoury2Eric Hawaux3Ksenija Limani4Krishna Narahari5Nicolas Sirtaine6Roland van Velthoven7Department of Urology, Jules Bordet Institute, 1 Rue Héger-Bordet, 1000 Brussels, BelgiumDepartment of Urology, Jules Bordet Institute, 1 Rue Héger-Bordet, 1000 Brussels, BelgiumDepartment of Urology, Jules Bordet Institute, 1 Rue Héger-Bordet, 1000 Brussels, BelgiumDepartment of Urology, Jules Bordet Institute, 1 Rue Héger-Bordet, 1000 Brussels, BelgiumDepartment of Urology, Jules Bordet Institute, 1 Rue Héger-Bordet, 1000 Brussels, BelgiumDepartment of Urology, Jules Bordet Institute, 1 Rue Héger-Bordet, 1000 Brussels, BelgiumDepartment of Anatomopathology, Jules Bordet Institute, 1 Rue Héger-Bordet, 1000 Brussels, BelgiumDepartment of Urology, Jules Bordet Institute, 1 Rue Héger-Bordet, 1000 Brussels, BelgiumObjectives. To compare prostate cancer detection rates of extended 2D versus 3D biopsies and to further assess the clinical impact of this method in day-to-day practice. Methods. We analyzed the data of a cohort of 220 consecutive patients with no prior history of prostate cancer who underwent an initial prostate biopsy in daily practice due to an abnormal PSA and/or DRE using, respectively, the classical 2D and the new 3D systems. All the biopsies were done by a single experienced operator using the same standardized protocol. Results. There was no significant difference in terms of age, total PSA, or prostate volume between the two groups. However, cancer detection rate was significantly higher using the 3D versus the 2D system, 50% versus 34% (P<0.05). There was no statistically significant difference while comparing the 2 groups in term of nonsignificant cancer detection. Conclusion. There is reasonable evidence demonstrating the superiority of the 3D-guided biopsies in detecting prostate cancers that would have been missed using the 2D extended protocol.http://dx.doi.org/10.1155/2013/783243 |
| spellingShingle | Alexandre Peltier Fouad Aoun Fouad El-Khoury Eric Hawaux Ksenija Limani Krishna Narahari Nicolas Sirtaine Roland van Velthoven 3D versus 2D Systematic Transrectal Ultrasound-Guided Prostate Biopsy: Higher Cancer Detection Rate in Clinical Practice Prostate Cancer |
| title | 3D versus 2D Systematic Transrectal Ultrasound-Guided Prostate Biopsy: Higher Cancer Detection Rate in Clinical Practice |
| title_full | 3D versus 2D Systematic Transrectal Ultrasound-Guided Prostate Biopsy: Higher Cancer Detection Rate in Clinical Practice |
| title_fullStr | 3D versus 2D Systematic Transrectal Ultrasound-Guided Prostate Biopsy: Higher Cancer Detection Rate in Clinical Practice |
| title_full_unstemmed | 3D versus 2D Systematic Transrectal Ultrasound-Guided Prostate Biopsy: Higher Cancer Detection Rate in Clinical Practice |
| title_short | 3D versus 2D Systematic Transrectal Ultrasound-Guided Prostate Biopsy: Higher Cancer Detection Rate in Clinical Practice |
| title_sort | 3d versus 2d systematic transrectal ultrasound guided prostate biopsy higher cancer detection rate in clinical practice |
| url | http://dx.doi.org/10.1155/2013/783243 |
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