Breast cancer risk associated with BRCA1 and BRCA2 pathogenic variants in the Eastern Chinese population

Breast cancer risk associated with BRCA1 and BRCA2 pathogenic variants in the Eastern Chinese population

Background: Population-based penetrance studies of breast cancer gene 1/2 (BRCA1/2) pathogenic or likely pathogenic (P/LP) variants in the Eastern Chinese population are currently lacking; thus, we aimed to investigate the penetrance of breast cancer and other malignant tumors among BRCA1/2 P/LP var...

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Bibliographic Details
Main Authors: Sanjian Yu, Xia Qiu, Zezhou Wang, Jialong Xiao, Hui Ji, Hailin Shan, Qing Shao, Heng Xia, Feng Cao, Jun Li, Cuixia Fu, Liqin Chen, Xiaofang Lu, Tingting Su, Qianqian Yu, Shengqun Hou, Honglian Wang, Ying Zheng, Zhimin Shao, Yun Liu, Zhen Hu
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Cancer Pathogenesis and Therapy
Subjects:
BRCA1/2 gene mutations
Breast cancer
Chinese population
Population-based studies
Online Access:http://www.sciencedirect.com/science/article/pii/S2949713224000260
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