INVESTIGATION OF NEUROPROTECTIVE ACTIVITY THIOPHANE INVOLUTIONAL CHORIORETINAL DEGENERATION IN RATS OXYS

INVESTIGATION OF NEUROPROTECTIVE ACTIVITY THIOPHANE INVOLUTIONAL CHORIORETINAL DEGENERATION IN RATS OXYS

The method of spontaneous and induced luminol -dependent chemiluminescence in homogenates of rat retinas OXYS registered increase in the generation of free radicals against decrease in total antioxidant  activity.  With  the  ultra-microscopic  and  quantitative  analysis  revealed  degenerative ret...

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Bibliographic Details
Main Authors: A. A. Zhdankina, G. A. Kon, M. B. Plotnikov, Ye. Yu. Varakuta, S. V. Logvinov, A. Ye. Prosenko, N. G. Kolosova
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2013-06-01
Series:Бюллетень сибирской медицины
Subjects:
morphological of retina
central chorioretinal degeneration
oxys
antioxidant activity
free radicals
luminol-dependent chemiluminescence
thiophane
Online Access:https://bulletin.ssmu.ru/jour/article/view/335
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Summary:The method of spontaneous and induced luminol -dependent chemiluminescence in homogenates of rat retinas OXYS registered increase in the generation of free radicals against decrease in total antioxidant  activity.  With  the  ultra-microscopic  and  quantitative  analysis  revealed  degenerative retinal neurons rats OXYS: the percentage increase in neurosensory cells with pyknosis of nuclei, hyperchromatic piknomorfnyh associative neurons and ganglion n eurons that have been modified on a light and dark type. Thiophane, limiting free radical reactions in the retina and protects retinal neurons from damage.
ISSN:1682-0363
1819-3684

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