Diagnosis and Treatment of Rheumatic Adverse Events Related to Immune Checkpoint Inhibitors

Immune checkpoint inhibitors (ICIs) have completely changed the treatment of cancer, and they also can cause multiple organ immune-related adverse reactions (irAEs). Among them, rheumatic irAE is less common, mainly including inflammatory arthritis, rheumatic myalgia/giant cell arteritis, inflammato...

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Main Authors: Yan Xiao, Lin Zeng, Qinglin Shen, Zhiyong Zhou, Zhifang Mao, Qin Wang, Xiquan Zhang, Yingliang Li, Weirong Yao
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2020/2640273
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author Yan Xiao
Lin Zeng
Qinglin Shen
Zhiyong Zhou
Zhifang Mao
Qin Wang
Xiquan Zhang
Yingliang Li
Weirong Yao
author_facet Yan Xiao
Lin Zeng
Qinglin Shen
Zhiyong Zhou
Zhifang Mao
Qin Wang
Xiquan Zhang
Yingliang Li
Weirong Yao
author_sort Yan Xiao
collection DOAJ
description Immune checkpoint inhibitors (ICIs) have completely changed the treatment of cancer, and they also can cause multiple organ immune-related adverse reactions (irAEs). Among them, rheumatic irAE is less common, mainly including inflammatory arthritis, rheumatic myalgia/giant cell arteritis, inflammatory myopathy, and Sjogren’s syndrome. For oncologists, rheumatism is a relatively new field, and early diagnosis and treatment is very important, and we need to work closely with experienced rheumatologists. In this review, we focused on the incidence, clinical characteristics, and treatment strategies of rheumatic irAE.
format Article
id doaj-art-43b0135eb7c5454f913cdc4db42ba203
institution Kabale University
issn 2314-8861
2314-7156
language English
publishDate 2020-01-01
publisher Wiley
record_format Article
series Journal of Immunology Research
spelling doaj-art-43b0135eb7c5454f913cdc4db42ba2032025-02-03T06:46:36ZengWileyJournal of Immunology Research2314-88612314-71562020-01-01202010.1155/2020/26402732640273Diagnosis and Treatment of Rheumatic Adverse Events Related to Immune Checkpoint InhibitorsYan Xiao0Lin Zeng1Qinglin Shen2Zhiyong Zhou3Zhifang Mao4Qin Wang5Xiquan Zhang6Yingliang Li7Weirong Yao8Department of Oncology, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Jiangxi, ChinaDepartment of Oncology, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Jiangxi, ChinaDepartment of Oncology, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Jiangxi, ChinaDepartment of Oncology, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Jiangxi, ChinaDepartment of Oncology, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Jiangxi, ChinaDepartment of Oncology, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Jiangxi, ChinaDepartment of Oncology, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Jiangxi, ChinaDepartment of General Surgery, The First Affiliated Hospital of Nanchang University, Jiangxi, ChinaDepartment of Oncology, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Jiangxi, ChinaImmune checkpoint inhibitors (ICIs) have completely changed the treatment of cancer, and they also can cause multiple organ immune-related adverse reactions (irAEs). Among them, rheumatic irAE is less common, mainly including inflammatory arthritis, rheumatic myalgia/giant cell arteritis, inflammatory myopathy, and Sjogren’s syndrome. For oncologists, rheumatism is a relatively new field, and early diagnosis and treatment is very important, and we need to work closely with experienced rheumatologists. In this review, we focused on the incidence, clinical characteristics, and treatment strategies of rheumatic irAE.http://dx.doi.org/10.1155/2020/2640273
spellingShingle Yan Xiao
Lin Zeng
Qinglin Shen
Zhiyong Zhou
Zhifang Mao
Qin Wang
Xiquan Zhang
Yingliang Li
Weirong Yao
Diagnosis and Treatment of Rheumatic Adverse Events Related to Immune Checkpoint Inhibitors
Journal of Immunology Research
title Diagnosis and Treatment of Rheumatic Adverse Events Related to Immune Checkpoint Inhibitors
title_full Diagnosis and Treatment of Rheumatic Adverse Events Related to Immune Checkpoint Inhibitors
title_fullStr Diagnosis and Treatment of Rheumatic Adverse Events Related to Immune Checkpoint Inhibitors
title_full_unstemmed Diagnosis and Treatment of Rheumatic Adverse Events Related to Immune Checkpoint Inhibitors
title_short Diagnosis and Treatment of Rheumatic Adverse Events Related to Immune Checkpoint Inhibitors
title_sort diagnosis and treatment of rheumatic adverse events related to immune checkpoint inhibitors
url http://dx.doi.org/10.1155/2020/2640273
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