Martini compatible coarse-grained model of polyethylenimine for pulmonary gene delivery
Abstract Pulmonary gene delivery has demonstrated high specificity for respiratory diseases, offering great control on dosage of therapeutics and side effects. On the other hand, intrinsic barriers in pulmonary systems impose new challenges such as crossing the pulmonary surfactant and evading mucus...
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Main Authors: | Graham Lunt, Niloofar Hashemi, Subhamoy Mahajan, Tian Tang |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-02-01
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Series: | Scientific Reports |
Subjects: | |
Online Access: | https://doi.org/10.1038/s41598-025-88848-x |
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