Deletion of AIF1 but not of YCA1/MCA1 protects Saccharomyces cerevisiae and Candida albicans cells from caspofungin-induced programmed cell death
Caspofungin was the first member of a new class of antifungals called echinocandins to be approved by a drug regulatory authority. Like the other echinocandins, caspofungin blocks the synthesis of β(1,3)-D-glucan of the fungal cell wall by inhibiting the enzyme, β(1,3)-D-glucan synthase. Loss of β(1...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Shared Science Publishers OG
2014-01-01
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| Series: | Microbial Cell |
| Subjects: | |
| Online Access: | http://microbialcell.com/researcharticles/deletion-of-aif1-but-not-of-yca1mca1-protects-saccharomyces-cerevisiae-and-candida-albicans-cells-from-caspofungin-induced-programmed-cell-death/ |
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