Pro-inflammatory mediator and cancer-associated chemokine CXCL8 as a prognostic indicator of tumor aggressiveness, angiogenesis, and disease progression with focus on therapeutic implications and recurrence monitoring

Pro-inflammatory mediator and cancer-associated chemokine CXCL8 as a prognostic indicator of tumor aggressiveness, angiogenesis, and disease progression with focus on therapeutic implications and recurrence monitoring

Background: Oral Squamous Cell Carcinoma (OSCC) is a prevalent malignancy characterized by high morbidity and mortality. Chronic inflammation within the tumor microenvironment plays a pivotal role in OSCC progression, with CXCL8 or interleukin-8 (IL-8) emerging as a significant cytokine implicated i...

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Bibliographic Details
Main Authors: Hema Shree K, Gayathri R, Vishnu Priya Veeraraghavan, Selvaraj J, Pratibha Ramani
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Oral Oncology Reports
Subjects:
IL-8
OSCC
Prognostic biomarker
Kaplan Meier analysis
ELISA
Online Access:http://www.sciencedirect.com/science/article/pii/S2772906025000111
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