Molecular evolution of peptide ligands with custom-tailored characteristics for targeting of glycostructures.

As an advanced approach to identify suitable targeting molecules required for various diagnostic and therapeutic interventions, we developed a procedure to devise peptides with customizable features by an iterative computer-assisted optimization strategy. An evolutionary algorithm was utilized to br...

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Bibliographic Details
Main Authors: Niels Röckendorf, Markus Borschbach, Andreas Frey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002800&type=printable
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