Clinical Outcome and Molecular Profile in Patients with <i>DDX41</i> Mutation Hot-Spots

Clinical Outcome and Molecular Profile in Patients with <i>DDX41</i> Mutation Hot-Spots

<b>Background/Objectives:</b> <i>DDX41</i>, DEAD-box RNA helicase 41 gene located on chromosome 5q25.3, is one of the most mutated genes in patients with germline predisposition to myeloid neoplasms. Germline and somatic mutations often have different locations and patterns o...

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Main Authors: Nadia Toumeh, Yazan Jabban, Ahmad Nanaa, Rong He, David Viswanatha, Dragan Jevremovic, James M. Foran, Cecilia Y. Arana Yi, Antoine N. Saliba, Mehrdad Hefazi Torghabeh, William J. Hogan, Mithun V. Shah, Abhishek A. Mangaonkar, Mrinal M. Patnaik, Hassan B. Alkhateeb, Aref Al-Kali
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Hematology Reports
Subjects:
<i>DDX41</i>
MDS
AML
Online Access:https://www.mdpi.com/2038-8330/17/3/26
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