Acute Lung Injury In Pneumonias

The review of the literature considers the etiology and pathogenesis of acute lung injury (ALI) in pneumonias. The development of ALI in pneumonias is largely determined by the properties of microorganisms and by the features of the macroor-ganism. The pathogenic properties of microorganisms lead to...

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Main Authors: V. V Moroz, A. M. Golubev, A. N. Kuzovlev, T. V. Smelaya
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2008-06-01
Series:Общая реаниматология
Online Access:https://www.reanimatology.com/rmt/article/view/760
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author V. V Moroz
A. M. Golubev
A. N. Kuzovlev
T. V. Smelaya
author_facet V. V Moroz
A. M. Golubev
A. N. Kuzovlev
T. V. Smelaya
author_sort V. V Moroz
collection DOAJ
description The review of the literature considers the etiology and pathogenesis of acute lung injury (ALI) in pneumonias. The development of ALI in pneumonias is largely determined by the properties of microorganisms and by the features of the macroor-ganism. The pathogenic properties of microorganisms lead to a damage to the air-blood barrier and to an impairment of the local protective mechanism in the lung. Alveolar damage, a systemic inflammatory reaction, and extracardiac pulmonary edema provoke ALI in pneumonias. The authors show it difficult to make a differential diagnosis and important to detect the early signs of ALI in pneumonias of various genesis. Transpulmonary thermodilution and identification of the markers of alveolar epithelial damage are promising methods. Key words: acute lung injury, pneumonia, sepsis, cytokines, transpul-monary thermodilution.
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institution Kabale University
issn 1813-9779
2411-7110
language English
publishDate 2008-06-01
publisher Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
record_format Article
series Общая реаниматология
spelling doaj-art-437f4122ba8f49df9aabc6e6b0139b012025-08-20T03:43:43ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102008-06-014310.15360/1813-9779-2008-3-106760Acute Lung Injury In PneumoniasV. V MorozA. M. GolubevA. N. KuzovlevT. V. SmelayaThe review of the literature considers the etiology and pathogenesis of acute lung injury (ALI) in pneumonias. The development of ALI in pneumonias is largely determined by the properties of microorganisms and by the features of the macroor-ganism. The pathogenic properties of microorganisms lead to a damage to the air-blood barrier and to an impairment of the local protective mechanism in the lung. Alveolar damage, a systemic inflammatory reaction, and extracardiac pulmonary edema provoke ALI in pneumonias. The authors show it difficult to make a differential diagnosis and important to detect the early signs of ALI in pneumonias of various genesis. Transpulmonary thermodilution and identification of the markers of alveolar epithelial damage are promising methods. Key words: acute lung injury, pneumonia, sepsis, cytokines, transpul-monary thermodilution.https://www.reanimatology.com/rmt/article/view/760
spellingShingle V. V Moroz
A. M. Golubev
A. N. Kuzovlev
T. V. Smelaya
Acute Lung Injury In Pneumonias
Общая реаниматология
title Acute Lung Injury In Pneumonias
title_full Acute Lung Injury In Pneumonias
title_fullStr Acute Lung Injury In Pneumonias
title_full_unstemmed Acute Lung Injury In Pneumonias
title_short Acute Lung Injury In Pneumonias
title_sort acute lung injury in pneumonias
url https://www.reanimatology.com/rmt/article/view/760
work_keys_str_mv AT vvmoroz acutelunginjuryinpneumonias
AT amgolubev acutelunginjuryinpneumonias
AT ankuzovlev acutelunginjuryinpneumonias
AT tvsmelaya acutelunginjuryinpneumonias