Antibacterial Effects of Natural Herbal Extracts on Streptococcus mutans: Can They Be Potential Additives in Dentifrices?

Background. Many plants or herbs exhibit potent antimicrobial activity against various microorganisms. They have no side effects and presumably act against and modulate the factors that are crucial for microbial survival or their activity. Streptococcus mutans is a pioneer bacteria implicated in den...

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Main Authors: Spoorthi Banavar Ravi, Sudarshini Nirupad, Prashanthi Chippagiri, Rohit Pandurangappa
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:International Journal of Dentistry
Online Access:http://dx.doi.org/10.1155/2017/4921614
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author Spoorthi Banavar Ravi
Sudarshini Nirupad
Prashanthi Chippagiri
Rohit Pandurangappa
author_facet Spoorthi Banavar Ravi
Sudarshini Nirupad
Prashanthi Chippagiri
Rohit Pandurangappa
author_sort Spoorthi Banavar Ravi
collection DOAJ
description Background. Many plants or herbs exhibit potent antimicrobial activity against various microorganisms. They have no side effects and presumably act against and modulate the factors that are crucial for microbial survival or their activity. Streptococcus mutans is a pioneer bacteria implicated in dental caries. This study aims to evaluate the antimicrobial activity of garlic bulbs, pudina leaves, and mango and eucalyptus twig extracts on Streptococcus mutans by evaluating their zone of inhibition and determining their minimum inhibitory concentration (MIC). Methods. Microbiological assay (well diffusion method) to determine zone of inhibition against pure forms of Streptococcus mutans was performed. The antibacterial effects of methanolic extracts of mango twigs, eucalyptus twigs, pudina leaves, and garlic bulbs were studied. Test compounds were further evaluated for their MIC. Results. Extracts derived from mango and eucalyptus twigs showed significant antibacterial effects at test concentrations. Pudina and garlic extracts did not show any significant antibacterial effects at similar concentrations. Upon further evaluation of the 2 positive compounds for their MIC, mango twigs demonstrated more antimicrobial potential than eucalyptus twigs at a lower concentration. Conclusion. Our observations indicated that the mango twig extracts possess higher antibacterial effects against Streptococcus mutans than other compounds at specific test concentration.
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issn 1687-8728
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publishDate 2017-01-01
publisher Wiley
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series International Journal of Dentistry
spelling doaj-art-437bf471873f4ac7a437abd614cbc7e22025-08-20T02:05:49ZengWileyInternational Journal of Dentistry1687-87281687-87362017-01-01201710.1155/2017/49216144921614Antibacterial Effects of Natural Herbal Extracts on Streptococcus mutans: Can They Be Potential Additives in Dentifrices?Spoorthi Banavar Ravi0Sudarshini Nirupad1Prashanthi Chippagiri2Rohit Pandurangappa3School of Dentistry, International Medical University, No. 126, Jalan 19/155B, Bukit Jalil, Kuala Lumpur, MalaysiaOral Pathology, Dr. Syamala Reddy Dental College Hospital and Research Centre, SGR College Main Road, Marathahalli Post, Bangalore, Karnataka, IndiaFaculty of Dentistry, MAHSA University, Kuala Lumpur, MalaysiaSchool of Dentistry, International Medical University, No. 126, Jalan 19/155B, Bukit Jalil, Kuala Lumpur, MalaysiaBackground. Many plants or herbs exhibit potent antimicrobial activity against various microorganisms. They have no side effects and presumably act against and modulate the factors that are crucial for microbial survival or their activity. Streptococcus mutans is a pioneer bacteria implicated in dental caries. This study aims to evaluate the antimicrobial activity of garlic bulbs, pudina leaves, and mango and eucalyptus twig extracts on Streptococcus mutans by evaluating their zone of inhibition and determining their minimum inhibitory concentration (MIC). Methods. Microbiological assay (well diffusion method) to determine zone of inhibition against pure forms of Streptococcus mutans was performed. The antibacterial effects of methanolic extracts of mango twigs, eucalyptus twigs, pudina leaves, and garlic bulbs were studied. Test compounds were further evaluated for their MIC. Results. Extracts derived from mango and eucalyptus twigs showed significant antibacterial effects at test concentrations. Pudina and garlic extracts did not show any significant antibacterial effects at similar concentrations. Upon further evaluation of the 2 positive compounds for their MIC, mango twigs demonstrated more antimicrobial potential than eucalyptus twigs at a lower concentration. Conclusion. Our observations indicated that the mango twig extracts possess higher antibacterial effects against Streptococcus mutans than other compounds at specific test concentration.http://dx.doi.org/10.1155/2017/4921614
spellingShingle Spoorthi Banavar Ravi
Sudarshini Nirupad
Prashanthi Chippagiri
Rohit Pandurangappa
Antibacterial Effects of Natural Herbal Extracts on Streptococcus mutans: Can They Be Potential Additives in Dentifrices?
International Journal of Dentistry
title Antibacterial Effects of Natural Herbal Extracts on Streptococcus mutans: Can They Be Potential Additives in Dentifrices?
title_full Antibacterial Effects of Natural Herbal Extracts on Streptococcus mutans: Can They Be Potential Additives in Dentifrices?
title_fullStr Antibacterial Effects of Natural Herbal Extracts on Streptococcus mutans: Can They Be Potential Additives in Dentifrices?
title_full_unstemmed Antibacterial Effects of Natural Herbal Extracts on Streptococcus mutans: Can They Be Potential Additives in Dentifrices?
title_short Antibacterial Effects of Natural Herbal Extracts on Streptococcus mutans: Can They Be Potential Additives in Dentifrices?
title_sort antibacterial effects of natural herbal extracts on streptococcus mutans can they be potential additives in dentifrices
url http://dx.doi.org/10.1155/2017/4921614
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AT prashanthichippagiri antibacterialeffectsofnaturalherbalextractsonstreptococcusmutanscantheybepotentialadditivesindentifrices
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