Dexmedetomidine as Part of a Multimodal Analgesic Treatment Regimen for Opioid Induced Hyperalgesia in a Patient with Significant Opioid Tolerance

Acute postoperative pain in patients with opioid tolerance creates a significant management challenge for anesthesiologists and pain medicine physicians. A multimodal approach is key; however other factors can complicate management such as opioid induced hyperalgesia. We present the case of a patien...

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Main Authors: Richard K. Patch III, Jason S. Eldrige, Susan M. Moeschler, Matthew J. Pingree
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Anesthesiology
Online Access:http://dx.doi.org/10.1155/2017/9876306
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author Richard K. Patch III
Jason S. Eldrige
Susan M. Moeschler
Matthew J. Pingree
author_facet Richard K. Patch III
Jason S. Eldrige
Susan M. Moeschler
Matthew J. Pingree
author_sort Richard K. Patch III
collection DOAJ
description Acute postoperative pain in patients with opioid tolerance creates a significant management challenge for anesthesiologists and pain medicine physicians. A multimodal approach is key; however other factors can complicate management such as opioid induced hyperalgesia. We present the case of a patient on large amounts of intrathecal opioids for chronic pain syndrome with opioid induced hyperalgesia after an exploratory laparotomy. Dexmedetomidine was utilized successfully as part of a controlled multimodal analgesic plan and should be a consideration for opioid tolerant patients experiencing opioid induced hyperalgesia.
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institution Kabale University
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series Case Reports in Anesthesiology
spelling doaj-art-437a8467590a41148393c4ffc506299f2025-02-03T01:24:01ZengWileyCase Reports in Anesthesiology2090-63822090-63902017-01-01201710.1155/2017/98763069876306Dexmedetomidine as Part of a Multimodal Analgesic Treatment Regimen for Opioid Induced Hyperalgesia in a Patient with Significant Opioid ToleranceRichard K. Patch III0Jason S. Eldrige1Susan M. Moeschler2Matthew J. Pingree3Division of Critical Care Medicine, Department of Anesthesiology & Perioperative Medicine and Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, USADivision of Pain Medicine, Department of Anesthesiology & Perioperative Medicine, Mayo Clinic, Rochester, MN, USADivision of Pain Medicine, Department of Anesthesiology & Perioperative Medicine, Mayo Clinic, Rochester, MN, USADepartment of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USAAcute postoperative pain in patients with opioid tolerance creates a significant management challenge for anesthesiologists and pain medicine physicians. A multimodal approach is key; however other factors can complicate management such as opioid induced hyperalgesia. We present the case of a patient on large amounts of intrathecal opioids for chronic pain syndrome with opioid induced hyperalgesia after an exploratory laparotomy. Dexmedetomidine was utilized successfully as part of a controlled multimodal analgesic plan and should be a consideration for opioid tolerant patients experiencing opioid induced hyperalgesia.http://dx.doi.org/10.1155/2017/9876306
spellingShingle Richard K. Patch III
Jason S. Eldrige
Susan M. Moeschler
Matthew J. Pingree
Dexmedetomidine as Part of a Multimodal Analgesic Treatment Regimen for Opioid Induced Hyperalgesia in a Patient with Significant Opioid Tolerance
Case Reports in Anesthesiology
title Dexmedetomidine as Part of a Multimodal Analgesic Treatment Regimen for Opioid Induced Hyperalgesia in a Patient with Significant Opioid Tolerance
title_full Dexmedetomidine as Part of a Multimodal Analgesic Treatment Regimen for Opioid Induced Hyperalgesia in a Patient with Significant Opioid Tolerance
title_fullStr Dexmedetomidine as Part of a Multimodal Analgesic Treatment Regimen for Opioid Induced Hyperalgesia in a Patient with Significant Opioid Tolerance
title_full_unstemmed Dexmedetomidine as Part of a Multimodal Analgesic Treatment Regimen for Opioid Induced Hyperalgesia in a Patient with Significant Opioid Tolerance
title_short Dexmedetomidine as Part of a Multimodal Analgesic Treatment Regimen for Opioid Induced Hyperalgesia in a Patient with Significant Opioid Tolerance
title_sort dexmedetomidine as part of a multimodal analgesic treatment regimen for opioid induced hyperalgesia in a patient with significant opioid tolerance
url http://dx.doi.org/10.1155/2017/9876306
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