A case of Progressive Multifocal Leukoencephalopathy in a HIV patient
Progressive Multifocal Leukoencephalopathy is a demyelinating disease of the brain which occurs as a result of reactivation of JC (John Cunningham) virus. It is the most common manifestation of JC virus and is typically seen in patients with an immunocompromised status. Here we will be disc...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sri Devaraj Urs Academy of Higher Education and Research
2022-06-01
|
| Series: | Journal of Clinical and Biomedical Sciences |
| Online Access: | https://jcbsonline.ac.in/articles/a-case-of-progressive-multifocal-leukoencephalopathy-in-a-hiv-patient |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849393934303756288 |
|---|---|
| author | . Aashish Anil Kumar Sakalecha Ravindra Naik A Chaithanya G R Varshitha R B Revanth |
| author_facet | . Aashish Anil Kumar Sakalecha Ravindra Naik A Chaithanya G R Varshitha R B Revanth |
| author_sort | . Aashish |
| collection | DOAJ |
| description | Progressive Multifocal Leukoencephalopathy is a demyelinating disease of the brain which occurs as a result of reactivation of JC (John Cunningham) virus. It is the most common manifestation of JC virus and is typically seen in patients with an immunocompromised status. Here we will be discussing about a 47 years old male patient who presented with altered sensorium and a past history of weakness in the right upper & lower limbs. Also, patient was found to be retropositive recently. He was referred to the department of Radio diagnosis for MRI (Magnetic Resonance Imaging) for further evaluation. The patient had multiple, asymmetric, white matter lesions in bilateral cerebral hemispheres, midbrain and even cerebellum. In the later course of the disease, the patient lost consciousness and ultimately succumbed to death due to multiorgan failure. The typical features of PML, followed by the role of imaging in diagnosis of PML and its peculiar features to differentiate from other similar white matter lesions of the brain are discussed. Keywords: Progressive Multifocal Leukoencephalopathy, subcortical U-fibers, HIV, Barbell sign |
| format | Article |
| id | doaj-art-437a7b6a09d7462ebc4ca51d2b1ba0a3 |
| institution | Kabale University |
| issn | 2231-4180 2319-2453 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | Sri Devaraj Urs Academy of Higher Education and Research |
| record_format | Article |
| series | Journal of Clinical and Biomedical Sciences |
| spelling | doaj-art-437a7b6a09d7462ebc4ca51d2b1ba0a32025-08-20T03:40:14ZengSri Devaraj Urs Academy of Higher Education and ResearchJournal of Clinical and Biomedical Sciences2231-41802319-24532022-06-01122717410.58739/jcbs/v12i2.2A case of Progressive Multifocal Leukoencephalopathy in a HIV patient. AashishAnil Kumar SakalechaRavindra Naik A Chaithanya G R Varshitha R B Revanth Progressive Multifocal Leukoencephalopathy is a demyelinating disease of the brain which occurs as a result of reactivation of JC (John Cunningham) virus. It is the most common manifestation of JC virus and is typically seen in patients with an immunocompromised status. Here we will be discussing about a 47 years old male patient who presented with altered sensorium and a past history of weakness in the right upper & lower limbs. Also, patient was found to be retropositive recently. He was referred to the department of Radio diagnosis for MRI (Magnetic Resonance Imaging) for further evaluation. The patient had multiple, asymmetric, white matter lesions in bilateral cerebral hemispheres, midbrain and even cerebellum. In the later course of the disease, the patient lost consciousness and ultimately succumbed to death due to multiorgan failure. The typical features of PML, followed by the role of imaging in diagnosis of PML and its peculiar features to differentiate from other similar white matter lesions of the brain are discussed. Keywords: Progressive Multifocal Leukoencephalopathy, subcortical U-fibers, HIV, Barbell signhttps://jcbsonline.ac.in/articles/a-case-of-progressive-multifocal-leukoencephalopathy-in-a-hiv-patient |
| spellingShingle | . Aashish Anil Kumar Sakalecha Ravindra Naik A Chaithanya G R Varshitha R B Revanth A case of Progressive Multifocal Leukoencephalopathy in a HIV patient Journal of Clinical and Biomedical Sciences |
| title | A case of Progressive Multifocal Leukoencephalopathy in a HIV patient |
| title_full | A case of Progressive Multifocal Leukoencephalopathy in a HIV patient |
| title_fullStr | A case of Progressive Multifocal Leukoencephalopathy in a HIV patient |
| title_full_unstemmed | A case of Progressive Multifocal Leukoencephalopathy in a HIV patient |
| title_short | A case of Progressive Multifocal Leukoencephalopathy in a HIV patient |
| title_sort | case of progressive multifocal leukoencephalopathy in a hiv patient |
| url | https://jcbsonline.ac.in/articles/a-case-of-progressive-multifocal-leukoencephalopathy-in-a-hiv-patient |
| work_keys_str_mv | AT aashish acaseofprogressivemultifocalleukoencephalopathyinahivpatient AT anilkumarsakalecha acaseofprogressivemultifocalleukoencephalopathyinahivpatient AT ravindranaik acaseofprogressivemultifocalleukoencephalopathyinahivpatient AT achaithanya acaseofprogressivemultifocalleukoencephalopathyinahivpatient AT grvarshitha acaseofprogressivemultifocalleukoencephalopathyinahivpatient AT rbrevanth acaseofprogressivemultifocalleukoencephalopathyinahivpatient AT aashish caseofprogressivemultifocalleukoencephalopathyinahivpatient AT anilkumarsakalecha caseofprogressivemultifocalleukoencephalopathyinahivpatient AT ravindranaik caseofprogressivemultifocalleukoencephalopathyinahivpatient AT achaithanya caseofprogressivemultifocalleukoencephalopathyinahivpatient AT grvarshitha caseofprogressivemultifocalleukoencephalopathyinahivpatient AT rbrevanth caseofprogressivemultifocalleukoencephalopathyinahivpatient |