An Important Biomarker in Patients with Bell’s Palsy: Serum Calprotectin
<i>Background and Objectives</i>: This study aimed to examine the relationship between serum calprotectin levels and facial paralysis in patients with Bell’s palsy and to determine its prognostic significance. <i>Materials and Methods</i>: This study included 40 patients diag...
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MDPI AG
2025-04-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/61/4/747 |
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| author | Cihan Türker Elif Emre Süleyman Aydın Mustafa Dalgıç Deniz Baklacı |
| author_facet | Cihan Türker Elif Emre Süleyman Aydın Mustafa Dalgıç Deniz Baklacı |
| author_sort | Cihan Türker |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: This study aimed to examine the relationship between serum calprotectin levels and facial paralysis in patients with Bell’s palsy and to determine its prognostic significance. <i>Materials and Methods</i>: This study included 40 patients diagnosed with Bell’s palsy and 20 healthy individuals as controls. The patients were categorized into three groups based on their response to treatment: complete response, partial response, and no response. Blood samples were taken before treatment and in the third month after treatment to measure C-reactive protein, white blood cell count, lymphocyte count, neutrophil count, neutrophil-to-lymphocyte ratio, and calprotectin levels. <i>Results</i>: Serum calprotectin levels were found to be elevated in patients with BP compared to the healthy controls; however, no significant correlation was observed between calprotectin levels and disease prognosis. <i>Conclusions</i>: The findings suggest that Bell’s palsy patients have elevated serum calprotectin levels compared to healthy individuals, indicating the potential use of calprotectin as a biomarker in Bell’s palsy. However, no significant difference in calprotectin levels was observed between patients with varying degrees of treatment response, suggesting that calprotectin may be limited in predicting disease prognosis. |
| format | Article |
| id | doaj-art-437542cabd1442aeb259094e3897277d |
| institution | DOAJ |
| issn | 1010-660X 1648-9144 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj-art-437542cabd1442aeb259094e3897277d2025-08-20T03:13:52ZengMDPI AGMedicina1010-660X1648-91442025-04-0161474710.3390/medicina61040747An Important Biomarker in Patients with Bell’s Palsy: Serum CalprotectinCihan Türker0Elif Emre1Süleyman Aydın2Mustafa Dalgıç3Deniz Baklacı4Department of Otolaryngology, Private Medical Hospital, Elazig 23040, TurkeyDepartment of Anatomy, Firat University Faculty of Medicine, Elazig 23200, TurkeyDepartment of Biochemistry, Firat University Faculty of Medicine, Elazig 23200, TurkeyDepartment of Otolaryngology, Ataturk State Hospital, Zonguldak 67030, TurkeyDepartment of Otolaryngology, Bulent Ecevit University Faculty of Medicine, Zonguldak 67000, Turkey<i>Background and Objectives</i>: This study aimed to examine the relationship between serum calprotectin levels and facial paralysis in patients with Bell’s palsy and to determine its prognostic significance. <i>Materials and Methods</i>: This study included 40 patients diagnosed with Bell’s palsy and 20 healthy individuals as controls. The patients were categorized into three groups based on their response to treatment: complete response, partial response, and no response. Blood samples were taken before treatment and in the third month after treatment to measure C-reactive protein, white blood cell count, lymphocyte count, neutrophil count, neutrophil-to-lymphocyte ratio, and calprotectin levels. <i>Results</i>: Serum calprotectin levels were found to be elevated in patients with BP compared to the healthy controls; however, no significant correlation was observed between calprotectin levels and disease prognosis. <i>Conclusions</i>: The findings suggest that Bell’s palsy patients have elevated serum calprotectin levels compared to healthy individuals, indicating the potential use of calprotectin as a biomarker in Bell’s palsy. However, no significant difference in calprotectin levels was observed between patients with varying degrees of treatment response, suggesting that calprotectin may be limited in predicting disease prognosis.https://www.mdpi.com/1648-9144/61/4/747Bell’s palsycalprotectinmarker |
| spellingShingle | Cihan Türker Elif Emre Süleyman Aydın Mustafa Dalgıç Deniz Baklacı An Important Biomarker in Patients with Bell’s Palsy: Serum Calprotectin Medicina Bell’s palsy calprotectin marker |
| title | An Important Biomarker in Patients with Bell’s Palsy: Serum Calprotectin |
| title_full | An Important Biomarker in Patients with Bell’s Palsy: Serum Calprotectin |
| title_fullStr | An Important Biomarker in Patients with Bell’s Palsy: Serum Calprotectin |
| title_full_unstemmed | An Important Biomarker in Patients with Bell’s Palsy: Serum Calprotectin |
| title_short | An Important Biomarker in Patients with Bell’s Palsy: Serum Calprotectin |
| title_sort | important biomarker in patients with bell s palsy serum calprotectin |
| topic | Bell’s palsy calprotectin marker |
| url | https://www.mdpi.com/1648-9144/61/4/747 |
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