The S2 subunit of spike encodes diverse targets for functional antibody responses to SARS-CoV-2.

The S2 subunit of spike encodes diverse targets for functional antibody responses to SARS-CoV-2.

The SARS-CoV-2 virus responsible for the COVID-19 global pandemic has exhibited a striking capacity for viral evolution that drives continued evasion from vaccine and infection-induced immune responses. Mutations in the receptor binding domain of the S1 subunit of the spike glycoprotein have led to...

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Main Authors: Jamie Guenthoer, Meghan E Garrett, Michelle Lilly, Delphine M Depierreux, Felicitas Ruiz, Margaret Chi, Caitlin I Stoddard, Vrasha Chohan, Zak A Yaffe, Kevin Sung, Duncan Ralph, Helen Y Chu, Frederick A Matsen, Julie Overbaugh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012383
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