Diabetic Striatopathy: A Rare Case Report of Chorea, Hyperglycemia, Basal Ganglia (C-H-BG) Syndrome

Chorea-hyperglycemia-basal ganglia syndrome is a rare complication of hyperglycemia and unilateral hemichorea-hemiballismus syndrome. Synonyms include diabetic striatopathy and non-ketotic hyperglycemic hemichorea. This occurs in 90% of individuals of Asian descent, particularly female patients with...

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Main Authors: Ifeoma Kwentoh, Phone Win, Fnu Allah Yar, Sabeena Shaikh, Tasheka McPherson, Terrence Henry, Leszek Pisinski, Raji Ayinla
Format: Article
Language:English
Published: American College of Physicians 2024-05-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2023.1342
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author Ifeoma Kwentoh
Phone Win
Fnu Allah Yar
Sabeena Shaikh
Tasheka McPherson
Terrence Henry
Leszek Pisinski
Raji Ayinla
author_facet Ifeoma Kwentoh
Phone Win
Fnu Allah Yar
Sabeena Shaikh
Tasheka McPherson
Terrence Henry
Leszek Pisinski
Raji Ayinla
author_sort Ifeoma Kwentoh
collection DOAJ
description Chorea-hyperglycemia-basal ganglia syndrome is a rare complication of hyperglycemia and unilateral hemichorea-hemiballismus syndrome. Synonyms include diabetic striatopathy and non-ketotic hyperglycemic hemichorea. This occurs in 90% of individuals of Asian descent, particularly female patients with type 2 diabetes. Diagnosis is made when the mean serum glucose level is 481.5 mg/dL, HbA1c level 14.4%, and serum osmolarity of 305.9 mmol/kg. It is managed with antipsychotic drugs and insulin. We report an 80-year-old man with diabetes who presented with disabling unintentional movements of his left extremities affecting his quality of life. Computed tomography and magnetic resonance imaging of the head demonstrated findings of diabetic striatopathy. Risperidone and glycemic control resolved the chorea like-movements.
format Article
id doaj-art-435ca4a2b5d346209d773002df984c9f
institution OA Journals
issn 2767-7664
language English
publishDate 2024-05-01
publisher American College of Physicians
record_format Article
series Annals of Internal Medicine: Clinical Cases
spelling doaj-art-435ca4a2b5d346209d773002df984c9f2025-08-20T02:27:20ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642024-05-013510.7326/aimcc.2023.1342Diabetic Striatopathy: A Rare Case Report of Chorea, Hyperglycemia, Basal Ganglia (C-H-BG) SyndromeIfeoma Kwentoh0Phone Win1Fnu Allah Yar2Sabeena Shaikh3Tasheka McPherson4Terrence Henry5Leszek Pisinski6Raji Ayinla71Harlem Hospital Center, New York, New York1Harlem Hospital Center, New York, New York1Harlem Hospital Center, New York, New York1Harlem Hospital Center, New York, New York1Harlem Hospital Center, New York, New York1Harlem Hospital Center, New York, New York1Harlem Hospital Center, New York, New York1Harlem Hospital Center, New York, New YorkChorea-hyperglycemia-basal ganglia syndrome is a rare complication of hyperglycemia and unilateral hemichorea-hemiballismus syndrome. Synonyms include diabetic striatopathy and non-ketotic hyperglycemic hemichorea. This occurs in 90% of individuals of Asian descent, particularly female patients with type 2 diabetes. Diagnosis is made when the mean serum glucose level is 481.5 mg/dL, HbA1c level 14.4%, and serum osmolarity of 305.9 mmol/kg. It is managed with antipsychotic drugs and insulin. We report an 80-year-old man with diabetes who presented with disabling unintentional movements of his left extremities affecting his quality of life. Computed tomography and magnetic resonance imaging of the head demonstrated findings of diabetic striatopathy. Risperidone and glycemic control resolved the chorea like-movements.https://www.acpjournals.org/doi/10.7326/aimcc.2023.1342
spellingShingle Ifeoma Kwentoh
Phone Win
Fnu Allah Yar
Sabeena Shaikh
Tasheka McPherson
Terrence Henry
Leszek Pisinski
Raji Ayinla
Diabetic Striatopathy: A Rare Case Report of Chorea, Hyperglycemia, Basal Ganglia (C-H-BG) Syndrome
Annals of Internal Medicine: Clinical Cases
title Diabetic Striatopathy: A Rare Case Report of Chorea, Hyperglycemia, Basal Ganglia (C-H-BG) Syndrome
title_full Diabetic Striatopathy: A Rare Case Report of Chorea, Hyperglycemia, Basal Ganglia (C-H-BG) Syndrome
title_fullStr Diabetic Striatopathy: A Rare Case Report of Chorea, Hyperglycemia, Basal Ganglia (C-H-BG) Syndrome
title_full_unstemmed Diabetic Striatopathy: A Rare Case Report of Chorea, Hyperglycemia, Basal Ganglia (C-H-BG) Syndrome
title_short Diabetic Striatopathy: A Rare Case Report of Chorea, Hyperglycemia, Basal Ganglia (C-H-BG) Syndrome
title_sort diabetic striatopathy a rare case report of chorea hyperglycemia basal ganglia c h bg syndrome
url https://www.acpjournals.org/doi/10.7326/aimcc.2023.1342
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