Diabetic Striatopathy: A Rare Case Report of Chorea, Hyperglycemia, Basal Ganglia (C-H-BG) Syndrome
Chorea-hyperglycemia-basal ganglia syndrome is a rare complication of hyperglycemia and unilateral hemichorea-hemiballismus syndrome. Synonyms include diabetic striatopathy and non-ketotic hyperglycemic hemichorea. This occurs in 90% of individuals of Asian descent, particularly female patients with...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American College of Physicians
2024-05-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2023.1342 |
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| Summary: | Chorea-hyperglycemia-basal ganglia syndrome is a rare complication of hyperglycemia and unilateral hemichorea-hemiballismus syndrome. Synonyms include diabetic striatopathy and non-ketotic hyperglycemic hemichorea. This occurs in 90% of individuals of Asian descent, particularly female patients with type 2 diabetes. Diagnosis is made when the mean serum glucose level is 481.5 mg/dL, HbA1c level 14.4%, and serum osmolarity of 305.9 mmol/kg. It is managed with antipsychotic drugs and insulin. We report an 80-year-old man with diabetes who presented with disabling unintentional movements of his left extremities affecting his quality of life. Computed tomography and magnetic resonance imaging of the head demonstrated findings of diabetic striatopathy. Risperidone and glycemic control resolved the chorea like-movements. |
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| ISSN: | 2767-7664 |