Distinct molecular properties and functions of small EV subpopulations isolated from human umbilical cord MSCs using tangential flow filtration combined with size exclusion chromatography

Distinct molecular properties and functions of small EV subpopulations isolated from human umbilical cord MSCs using tangential flow filtration combined with size exclusion chromatography

Abstract As functional derivatives of mesenchymal stem cells (MSCs), small extracellular vesicles (sEVs) have garnered significant attention and application in regenerative medicine. However, the technical limitations for large‐scale isolation of sEVs and their heterogeneous nature have added comple...

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Bibliographic Details
Main Authors: Wei Liu, Xinyu Wang, Yating Chen, Jiapei Yuan, Huiyu Zhang, Xin Jin, Yuying Jiang, Junjing Cao, Zibin Wang, Shuo Yang, Bingwei Wang, Tinghe Wu, Jing Li
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Journal of Extracellular Vesicles
Subjects:
mesenchymal stem cells
sEVs
size exclusion chromatography
tangential flow filtration
targeted therapies
Online Access:https://doi.org/10.1002/jev2.70029
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