Clinical Trial of Sinudrain Haft Bahr Solution for Symptom Management in Mild to Moderate COVID-19
Introduction: The COVID-19 pandemic, caused by the coronavirus, has been declared a global health emergency by the World Health Organization (WHO). This virus primarily affects the respiratory system, and affordable treatments for mild to moderate cases are urgently needed. Sinudrain Haft Bahr, a so...
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SBMU Journals
2024-01-01
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| author | Hamid Chegni |
| author_facet | Hamid Chegni |
| author_sort | Hamid Chegni |
| collection | DOAJ |
| description | Introduction: The COVID-19 pandemic, caused by the coronavirus, has been declared a global health emergency by the World Health Organization (WHO). This virus primarily affects the respiratory system, and affordable treatments for mild to moderate cases are urgently needed. Sinudrain Haft Bahr, a solution with antiseptic properties, was evaluated for its potential to alleviate COVID-19 symptoms.
Materials and Methods: A clinical trial was conducted on 61 COVID-19 patients at Taleghani Hospital, Tehran. After a medical evaluation and analysis of symptoms, participants were randomized 1:1 (intervention vs. control) using admission code parity. The intervention group received Sinudrain, while the control group received routine medications from the national protocol. The drug was administered by gargling the solution three times a day and spraying it inside the nose six times a day. Patients' clinical symptoms were monitored on the first, third, and fifth days.
Results: Sinudrain significantly reduced cough (45%), sore throat (41%), and shortness of breath (32%) versus controls (all p<0.05). No effect was observed on fever, loss of smell, or digestive symptoms.
Conclusion: Sinudrain is a promising adjunctive therapy for COVID-19 respiratory symptoms, with advantages in cost, availability, and safety. Further trials are warranted.
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| format | Article |
| id | doaj-art-4357a85b04bb4c4faa83f3591fb7b93c |
| institution | Kabale University |
| issn | 2783-1264 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | SBMU Journals |
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| series | Archives of Advances in Biosciences |
| spelling | doaj-art-4357a85b04bb4c4faa83f3591fb7b93c2025-08-20T03:48:06ZengSBMU JournalsArchives of Advances in Biosciences2783-12642024-01-01151111https://doi.org/10.22037/aab.v15i1.47585Clinical Trial of Sinudrain Haft Bahr Solution for Symptom Management in Mild to Moderate COVID-19Hamid Chegni 0https://orcid.org/0000-0003-4965-2424Department of Medical Laboratory Science, Shahid Beheshti University of Medical Sciences, Tehran, IranIntroduction: The COVID-19 pandemic, caused by the coronavirus, has been declared a global health emergency by the World Health Organization (WHO). This virus primarily affects the respiratory system, and affordable treatments for mild to moderate cases are urgently needed. Sinudrain Haft Bahr, a solution with antiseptic properties, was evaluated for its potential to alleviate COVID-19 symptoms. Materials and Methods: A clinical trial was conducted on 61 COVID-19 patients at Taleghani Hospital, Tehran. After a medical evaluation and analysis of symptoms, participants were randomized 1:1 (intervention vs. control) using admission code parity. The intervention group received Sinudrain, while the control group received routine medications from the national protocol. The drug was administered by gargling the solution three times a day and spraying it inside the nose six times a day. Patients' clinical symptoms were monitored on the first, third, and fifth days. Results: Sinudrain significantly reduced cough (45%), sore throat (41%), and shortness of breath (32%) versus controls (all p<0.05). No effect was observed on fever, loss of smell, or digestive symptoms. Conclusion: Sinudrain is a promising adjunctive therapy for COVID-19 respiratory symptoms, with advantages in cost, availability, and safety. Further trials are warranted. covid-19sinudrain haft bahrrandomized controlled trialrespiratory symptomsnasal spray |
| spellingShingle | Hamid Chegni Clinical Trial of Sinudrain Haft Bahr Solution for Symptom Management in Mild to Moderate COVID-19 Archives of Advances in Biosciences covid-19 sinudrain haft bahr randomized controlled trial respiratory symptoms nasal spray |
| title | Clinical Trial of Sinudrain Haft Bahr Solution for Symptom Management in Mild to Moderate COVID-19 |
| title_full | Clinical Trial of Sinudrain Haft Bahr Solution for Symptom Management in Mild to Moderate COVID-19 |
| title_fullStr | Clinical Trial of Sinudrain Haft Bahr Solution for Symptom Management in Mild to Moderate COVID-19 |
| title_full_unstemmed | Clinical Trial of Sinudrain Haft Bahr Solution for Symptom Management in Mild to Moderate COVID-19 |
| title_short | Clinical Trial of Sinudrain Haft Bahr Solution for Symptom Management in Mild to Moderate COVID-19 |
| title_sort | clinical trial of sinudrain haft bahr solution for symptom management in mild to moderate covid 19 |
| topic | covid-19 sinudrain haft bahr randomized controlled trial respiratory symptoms nasal spray |
| work_keys_str_mv | AT hamidchegni clinicaltrialofsinudrainhaftbahrsolutionforsymptommanagementinmildtomoderatecovid19 |