Programmed Host Cell Death and Infectious Process of Mycoplasma

A common characteristic of Mycoplasma diseases is their chronicity, Mycoplasma spp. infection have been frequently associated with upper respiratory infections, chronic lung disease , asthma, meningeal encephalitis, mastitis, arthritis, heart problems, sterility, bone problems , oviduct dysfunctions...

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Main Authors: Alaa Abed, Ali Al-Iedani, Ahmed Neamah
Format: Article
Language:English
Published: College of Veterinary Medicine, University of Basrah, Iraq 2022-09-01
Series:Basrah Journal of Veterinary Research
Subjects:
Online Access:https://bjvr.uobasrah.edu.iq/article_175774_78ff1dedba469aba3c65087c2a38d9a8.pdf
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author Alaa Abed
Ali Al-Iedani
Ahmed Neamah
author_facet Alaa Abed
Ali Al-Iedani
Ahmed Neamah
author_sort Alaa Abed
collection DOAJ
description A common characteristic of Mycoplasma diseases is their chronicity, Mycoplasma spp. infection have been frequently associated with upper respiratory infections, chronic lung disease , asthma, meningeal encephalitis, mastitis, arthritis, heart problems, sterility, bone problems , oviduct dysfunctions and death in human and different animal species. In former years, changeable expression of membrane antigens has been detected in a number of Mycoplasma spp., resulting in the assumption that immune prevarication may be an important part of the their infection and pathogenesis. It has been determined how the attachment organelle, which mediates the complicated interactions between various adhesins and auxiliary adhesion proteins to mediate the critical first stage of cytoadherence to respiratory tract epithelium. Additionally, it has been demonstrated that inflammatory cytokines cause tissue damage by intracellular localization, direct cytotoxicity, and activation of the inflammatory cascade via Toll-like receptors (TLRs), and inflammosome activation, which causes air passage inflammation. All of these play crucial roles in the infectious process. This paper seeks to provide a thorough assessment of recent developments in our understanding of Mycoplasma pathogenesis with the understanding of its virulence mechanisms.
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publishDate 2022-09-01
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spelling doaj-art-4356f9fce0364aa784c32a0b1e2dce032025-08-20T02:30:31ZengCollege of Veterinary Medicine, University of Basrah, IraqBasrah Journal of Veterinary Research1813-84972410-84562022-09-01213425710.23975/bjvetr.2022.175774175774Programmed Host Cell Death and Infectious Process of MycoplasmaAlaa Abed0Ali Al-Iedani1Ahmed Neamah2Department of Microbiology and Parasitology, College of Veterinary Medicine, University of Basrah, IraqDepartment of Pathology and Poultry Diseases, College of Veterinary Medicine, University of Al-Qadisiyah, Iraq.Unit of Zoonotic Diseases, College of Veterinary Medicine, University of Al-Qadisiyah, Iraq.A common characteristic of Mycoplasma diseases is their chronicity, Mycoplasma spp. infection have been frequently associated with upper respiratory infections, chronic lung disease , asthma, meningeal encephalitis, mastitis, arthritis, heart problems, sterility, bone problems , oviduct dysfunctions and death in human and different animal species. In former years, changeable expression of membrane antigens has been detected in a number of Mycoplasma spp., resulting in the assumption that immune prevarication may be an important part of the their infection and pathogenesis. It has been determined how the attachment organelle, which mediates the complicated interactions between various adhesins and auxiliary adhesion proteins to mediate the critical first stage of cytoadherence to respiratory tract epithelium. Additionally, it has been demonstrated that inflammatory cytokines cause tissue damage by intracellular localization, direct cytotoxicity, and activation of the inflammatory cascade via Toll-like receptors (TLRs), and inflammosome activation, which causes air passage inflammation. All of these play crucial roles in the infectious process. This paper seeks to provide a thorough assessment of recent developments in our understanding of Mycoplasma pathogenesis with the understanding of its virulence mechanisms.https://bjvr.uobasrah.edu.iq/article_175774_78ff1dedba469aba3c65087c2a38d9a8.pdfmycoplasmasinfectious processprogrammed cell deathapoptosis
spellingShingle Alaa Abed
Ali Al-Iedani
Ahmed Neamah
Programmed Host Cell Death and Infectious Process of Mycoplasma
Basrah Journal of Veterinary Research
mycoplasmas
infectious process
programmed cell death
apoptosis
title Programmed Host Cell Death and Infectious Process of Mycoplasma
title_full Programmed Host Cell Death and Infectious Process of Mycoplasma
title_fullStr Programmed Host Cell Death and Infectious Process of Mycoplasma
title_full_unstemmed Programmed Host Cell Death and Infectious Process of Mycoplasma
title_short Programmed Host Cell Death and Infectious Process of Mycoplasma
title_sort programmed host cell death and infectious process of mycoplasma
topic mycoplasmas
infectious process
programmed cell death
apoptosis
url https://bjvr.uobasrah.edu.iq/article_175774_78ff1dedba469aba3c65087c2a38d9a8.pdf
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