PrPC Glycoprotein Is Indispensable for Maintenance of Skeletal Muscle Homeostasis During Aging

ABSTRACT Background The cellular prion protein (PrPC), a glycoprotein encoded by the PRNP gene, is known to modulate muscle mass and exercise capacity. However, the role of PrPC in the maintenance and regeneration of skeletal muscle during ageing remains unclear. Methods This study investigated the...

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Bibliographic Details
Main Authors: Wenduo Liu, Thi Thu Trang Kieu, Zilin Wang, Hyun‐Jaung Sim, Seohyeong Lee, Jeong‐Chae Lee, Yoonjung Park, Sang Hyun Kim, Sung‐Ho Kook
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Journal of Cachexia, Sarcopenia and Muscle
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Online Access:https://doi.org/10.1002/jcsm.13706
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