Evaluation of Osteoarticular Involvement Associated with Brucellosis in Children

Aim: Brucellosis is a significant public health problem with high morbidity. Its most frequent complication is osteoarticular involvement. The study aimed to evaluate the relationship of osteoarticular involvement with clinical features and prognosis in children with brucellosis.Material and Methods...

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Main Authors: Tuğba Nur Kutlu Beşeren, Zafer Bıçakçı, Müferet Ergüven, Hayrunnisa Bekis Bozkurt
Format: Article
Language:English
Published: Duzce University 2025-04-01
Series:Düzce Tıp Fakültesi Dergisi
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Online Access:https://dergipark.org.tr/en/download/article-file/4339007
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author Tuğba Nur Kutlu Beşeren
Zafer Bıçakçı
Müferet Ergüven
Hayrunnisa Bekis Bozkurt
author_facet Tuğba Nur Kutlu Beşeren
Zafer Bıçakçı
Müferet Ergüven
Hayrunnisa Bekis Bozkurt
author_sort Tuğba Nur Kutlu Beşeren
collection DOAJ
description Aim: Brucellosis is a significant public health problem with high morbidity. Its most frequent complication is osteoarticular involvement. The study aimed to evaluate the relationship of osteoarticular involvement with clinical features and prognosis in children with brucellosis.Material and Methods: This retrospective study included pediatric patients between the ages of 1 and 18 years who were hospitalized and diagnosed with brucellosis between 2015 and 2020, and were regularly followed up. and all their findings and osteoarticular involvement data within the last two years were recorded. Clinical features, laboratory findings, osteoarticular involvement, and relapse rates of the patients were evaluated.Results: A total of 80 patients were included study. During the follow-up period, relapse developed in 14 (17.5%) patients. The most commonly affected joints were right (40%, n=32) and left (26.3%, n=21) hips, then right (27.5%, n=22) and left (23.8%, n=19) knees. Shoulder joint involvement rates and C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), alanine transaminase (ALT), and aspartate aminotransferase (AST) levels were statistically significantly higher in the relapse group (p=0.016, p=0.003, p=0.001, p
format Article
id doaj-art-43543e47de014cee94a67623e6afc4dd
institution OA Journals
issn 1307-671X
language English
publishDate 2025-04-01
publisher Duzce University
record_format Article
series Düzce Tıp Fakültesi Dergisi
spelling doaj-art-43543e47de014cee94a67623e6afc4dd2025-08-20T02:18:57ZengDuzce UniversityDüzce Tıp Fakültesi Dergisi1307-671X2025-04-01271758010.18678/dtfd.157916797Evaluation of Osteoarticular Involvement Associated with Brucellosis in ChildrenTuğba Nur Kutlu Beşeren0https://orcid.org/0000-0003-4583-0860Zafer Bıçakçı1https://orcid.org/0000-0002-1321-4708Müferet Ergüven2https://orcid.org/0000-0002-3255-1208Hayrunnisa Bekis Bozkurt3https://orcid.org/0000-0001-8642-4872KAFKAS ÜNİVERSİTESİ, TIP FAKÜLTESİKAFKAS ÜNİVERSİTESİ, TIP FAKÜLTESİDÜZCE ÜNİVERSİTESİ, TIP FAKÜLTESİSAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL ÜMRANİYE SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİAim: Brucellosis is a significant public health problem with high morbidity. Its most frequent complication is osteoarticular involvement. The study aimed to evaluate the relationship of osteoarticular involvement with clinical features and prognosis in children with brucellosis.Material and Methods: This retrospective study included pediatric patients between the ages of 1 and 18 years who were hospitalized and diagnosed with brucellosis between 2015 and 2020, and were regularly followed up. and all their findings and osteoarticular involvement data within the last two years were recorded. Clinical features, laboratory findings, osteoarticular involvement, and relapse rates of the patients were evaluated.Results: A total of 80 patients were included study. During the follow-up period, relapse developed in 14 (17.5%) patients. The most commonly affected joints were right (40%, n=32) and left (26.3%, n=21) hips, then right (27.5%, n=22) and left (23.8%, n=19) knees. Shoulder joint involvement rates and C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), alanine transaminase (ALT), and aspartate aminotransferase (AST) levels were statistically significantly higher in the relapse group (p=0.016, p=0.003, p=0.001, phttps://dergipark.org.tr/en/download/article-file/4339007brusellozosteoartritsakroiliak eklemomuz eklemirelapsbrucellosisosteoarthritissacroiliac jointshoulder jointrelapse
spellingShingle Tuğba Nur Kutlu Beşeren
Zafer Bıçakçı
Müferet Ergüven
Hayrunnisa Bekis Bozkurt
Evaluation of Osteoarticular Involvement Associated with Brucellosis in Children
Düzce Tıp Fakültesi Dergisi
bruselloz
osteoartrit
sakroiliak eklem
omuz eklemi
relaps
brucellosis
osteoarthritis
sacroiliac joint
shoulder joint
relapse
title Evaluation of Osteoarticular Involvement Associated with Brucellosis in Children
title_full Evaluation of Osteoarticular Involvement Associated with Brucellosis in Children
title_fullStr Evaluation of Osteoarticular Involvement Associated with Brucellosis in Children
title_full_unstemmed Evaluation of Osteoarticular Involvement Associated with Brucellosis in Children
title_short Evaluation of Osteoarticular Involvement Associated with Brucellosis in Children
title_sort evaluation of osteoarticular involvement associated with brucellosis in children
topic bruselloz
osteoartrit
sakroiliak eklem
omuz eklemi
relaps
brucellosis
osteoarthritis
sacroiliac joint
shoulder joint
relapse
url https://dergipark.org.tr/en/download/article-file/4339007
work_keys_str_mv AT tugbanurkutlubeseren evaluationofosteoarticularinvolvementassociatedwithbrucellosisinchildren
AT zaferbıcakcı evaluationofosteoarticularinvolvementassociatedwithbrucellosisinchildren
AT mufereterguven evaluationofosteoarticularinvolvementassociatedwithbrucellosisinchildren
AT hayrunnisabekisbozkurt evaluationofosteoarticularinvolvementassociatedwithbrucellosisinchildren