Multiple Cutaneous Angiosarcomas after Breast Conserving Surgery and Bilateral Adjuvant Radiotherapy: An Unusual Case and Review of the Literature
Breast angiosarcomas (BAs) are rare but serious events that may arise after radiation exposure. Disease outcome is poor, with high risk of local and distant failure. Recurrences are frequent also after resection with negative margins. The spectrum of vascular proliferations associated with radiother...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2014/413030 |
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| author | Icro Meattini Raffaella Santi Daniele Scartoni Irene Giacomelli Carla De Luca Cardillo Vieri Scotti Donato Casella Roberta Simoncini Lorenzo Orzalesi Jacopo Nori Milena Paglierani Lorenzo Livi |
| author_facet | Icro Meattini Raffaella Santi Daniele Scartoni Irene Giacomelli Carla De Luca Cardillo Vieri Scotti Donato Casella Roberta Simoncini Lorenzo Orzalesi Jacopo Nori Milena Paglierani Lorenzo Livi |
| author_sort | Icro Meattini |
| collection | DOAJ |
| description | Breast angiosarcomas (BAs) are rare but serious events that may arise after radiation exposure. Disease outcome is poor, with high risk of local and distant failure. Recurrences are frequent also after resection with negative margins. The spectrum of vascular proliferations associated with radiotherapy in the setting of breast cancer has expanded, including radiation-associated atypical vascular lesions (AVLs) of the breast skin as a rare, but well-recognized, entity. Although pursuing a benign behavior, AVLs have been regarded as possible precursors of postradiation BAs. We report an unusual case of a 71-year-old woman affected by well-differentiated bilateral cutaneous BA, diagnosed 1.9 years after adjuvant RT for synchronous bilateral breast cancer. Whole-life clinical followup is of crucial importance in breast cancer patients. |
| format | Article |
| id | doaj-art-4349c2dbd4424f7c81c8ca74ca706668 |
| institution | OA Journals |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-4349c2dbd4424f7c81c8ca74ca7066682025-08-20T02:37:58ZengWileyCase Reports in Oncological Medicine2090-67062090-67142014-01-01201410.1155/2014/413030413030Multiple Cutaneous Angiosarcomas after Breast Conserving Surgery and Bilateral Adjuvant Radiotherapy: An Unusual Case and Review of the LiteratureIcro Meattini0Raffaella Santi1Daniele Scartoni2Irene Giacomelli3Carla De Luca Cardillo4Vieri Scotti5Donato Casella6Roberta Simoncini7Lorenzo Orzalesi8Jacopo Nori9Milena Paglierani10Lorenzo Livi11Department of Radiation-Oncology, University of Florence, Largo G.A. Brambilla 3, 50134 Florence, ItalyDivision of Pathological Anatomy, University of Florence, Largo G.A. Brambilla 3, 50134 Florence, ItalyDepartment of Radiation-Oncology, University of Florence, Largo G.A. Brambilla 3, 50134 Florence, ItalyDepartment of Radiation-Oncology, University of Florence, Largo G.A. Brambilla 3, 50134 Florence, ItalyDepartment of Radiation-Oncology, University of Florence, Largo G.A. Brambilla 3, 50134 Florence, ItalyDepartment of Radiation-Oncology, University of Florence, Largo G.A. Brambilla 3, 50134 Florence, ItalyDepartment of Surgery, University of Florence, Largo G.A. Brambilla 3, 50134 Florence, ItalyDepartment of Surgery, University of Florence, Largo G.A. Brambilla 3, 50134 Florence, ItalyDepartment of Surgery, University of Florence, Largo G.A. Brambilla 3, 50134 Florence, ItalyDiagnostic Senology Unit, University of Florence, Largo G.A. Brambilla 3, 50134 Florence, ItalyDivision of Pathological Anatomy, University of Florence, Largo G.A. Brambilla 3, 50134 Florence, ItalyDepartment of Radiation-Oncology, University of Florence, Largo G.A. Brambilla 3, 50134 Florence, ItalyBreast angiosarcomas (BAs) are rare but serious events that may arise after radiation exposure. Disease outcome is poor, with high risk of local and distant failure. Recurrences are frequent also after resection with negative margins. The spectrum of vascular proliferations associated with radiotherapy in the setting of breast cancer has expanded, including radiation-associated atypical vascular lesions (AVLs) of the breast skin as a rare, but well-recognized, entity. Although pursuing a benign behavior, AVLs have been regarded as possible precursors of postradiation BAs. We report an unusual case of a 71-year-old woman affected by well-differentiated bilateral cutaneous BA, diagnosed 1.9 years after adjuvant RT for synchronous bilateral breast cancer. Whole-life clinical followup is of crucial importance in breast cancer patients.http://dx.doi.org/10.1155/2014/413030 |
| spellingShingle | Icro Meattini Raffaella Santi Daniele Scartoni Irene Giacomelli Carla De Luca Cardillo Vieri Scotti Donato Casella Roberta Simoncini Lorenzo Orzalesi Jacopo Nori Milena Paglierani Lorenzo Livi Multiple Cutaneous Angiosarcomas after Breast Conserving Surgery and Bilateral Adjuvant Radiotherapy: An Unusual Case and Review of the Literature Case Reports in Oncological Medicine |
| title | Multiple Cutaneous Angiosarcomas after Breast Conserving Surgery and Bilateral Adjuvant Radiotherapy: An Unusual Case and Review of the Literature |
| title_full | Multiple Cutaneous Angiosarcomas after Breast Conserving Surgery and Bilateral Adjuvant Radiotherapy: An Unusual Case and Review of the Literature |
| title_fullStr | Multiple Cutaneous Angiosarcomas after Breast Conserving Surgery and Bilateral Adjuvant Radiotherapy: An Unusual Case and Review of the Literature |
| title_full_unstemmed | Multiple Cutaneous Angiosarcomas after Breast Conserving Surgery and Bilateral Adjuvant Radiotherapy: An Unusual Case and Review of the Literature |
| title_short | Multiple Cutaneous Angiosarcomas after Breast Conserving Surgery and Bilateral Adjuvant Radiotherapy: An Unusual Case and Review of the Literature |
| title_sort | multiple cutaneous angiosarcomas after breast conserving surgery and bilateral adjuvant radiotherapy an unusual case and review of the literature |
| url | http://dx.doi.org/10.1155/2014/413030 |
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