Femoral neck system versus cannulated screws combined with medial plate for femoral neck fractures in young and middle-aged patients: a prospective multicenter randomized controlled trial

Abstract Background Femoral neck system (FNS) and cannulated screws combined with medial plate (CS with medial plate) both are commonly used internal fixation for femoral neck fractures in recent years. There is a debate that which is the better choice for young and middle-aged patients with femoral...

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Main Authors: Mingyu Wen, Shengying Wang, Lihua Wang, Yuhai Wang, Shiyou Dai, Wen Liu, Xiao Fan
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-025-05972-0
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author Mingyu Wen
Shengying Wang
Lihua Wang
Yuhai Wang
Shiyou Dai
Wen Liu
Xiao Fan
author_facet Mingyu Wen
Shengying Wang
Lihua Wang
Yuhai Wang
Shiyou Dai
Wen Liu
Xiao Fan
author_sort Mingyu Wen
collection DOAJ
description Abstract Background Femoral neck system (FNS) and cannulated screws combined with medial plate (CS with medial plate) both are commonly used internal fixation for femoral neck fractures in recent years. There is a debate that which is the better choice for young and middle-aged patients with femoral neck fractures. The objective of the study is to compare clinical effects of FNS and CS with medial plate on young and middle-aged patients with femoral neck fractures by a prospective multicenter randomized controlled trial for the first time. Methods Patients between 18 and 65 years old with femoral neck fractures were allocated to FNS fixation and CS with medial plate fixation with 2 years follow-up. The primary outcomes included fracture bone union rate and Harris hip score. The secondary outcomes included Garden’s alignment index, surgical data, Barthel index, visual analogue scale (VAS), gait analysis and complications during follow-up. Statistical analysis was performed by multiple linear regression and logistics regression. Results 165 patients in FNS group and 166 patients in CS with medial plate group were analyzed finally. There was no statistical difference in bone union rate, Garden’s alignment index, Barthel index, gait analysis between two groups. The FNS group had a higher Harris hip score at 3 months after operation (P < 0.05), lower surgical data including operation time, intraoperative blood loss and fluoroscopy frequency (P < 0.001) and lower VAS at 1 month after operation (P < 0.05) than that of CS with medial plate group, but no significant difference at 3, 6, 12, and 24 months. There was no statistical difference in the incidence of complications between groups, except the incidence of coxa vara, which is higher in FNS group (P < 0.05). Conclusions For young and middle-aged patients with femoral neck fractures, both FNS and CS combined with a medial plate are effective. Trial registration ChiCTR2100042960, registered 1 February 2021, http://www.chictr.org.cn .
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spelling doaj-art-4339c1e3aa4248aab631619f5f2e6a2e2025-08-20T03:26:43ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2025-06-0120111110.1186/s13018-025-05972-0Femoral neck system versus cannulated screws combined with medial plate for femoral neck fractures in young and middle-aged patients: a prospective multicenter randomized controlled trialMingyu Wen0Shengying Wang1Lihua Wang2Yuhai Wang3Shiyou Dai4Wen Liu5Xiao Fan6Qingdao UniversityQingdao Municipal HospitalFuzhou Second HospitalPeople’s Hospital of Ningxia Hui Autonomous RegionQingdao Municipal HospitalQingdao Municipal HospitalQingdao Municipal HospitalAbstract Background Femoral neck system (FNS) and cannulated screws combined with medial plate (CS with medial plate) both are commonly used internal fixation for femoral neck fractures in recent years. There is a debate that which is the better choice for young and middle-aged patients with femoral neck fractures. The objective of the study is to compare clinical effects of FNS and CS with medial plate on young and middle-aged patients with femoral neck fractures by a prospective multicenter randomized controlled trial for the first time. Methods Patients between 18 and 65 years old with femoral neck fractures were allocated to FNS fixation and CS with medial plate fixation with 2 years follow-up. The primary outcomes included fracture bone union rate and Harris hip score. The secondary outcomes included Garden’s alignment index, surgical data, Barthel index, visual analogue scale (VAS), gait analysis and complications during follow-up. Statistical analysis was performed by multiple linear regression and logistics regression. Results 165 patients in FNS group and 166 patients in CS with medial plate group were analyzed finally. There was no statistical difference in bone union rate, Garden’s alignment index, Barthel index, gait analysis between two groups. The FNS group had a higher Harris hip score at 3 months after operation (P < 0.05), lower surgical data including operation time, intraoperative blood loss and fluoroscopy frequency (P < 0.001) and lower VAS at 1 month after operation (P < 0.05) than that of CS with medial plate group, but no significant difference at 3, 6, 12, and 24 months. There was no statistical difference in the incidence of complications between groups, except the incidence of coxa vara, which is higher in FNS group (P < 0.05). Conclusions For young and middle-aged patients with femoral neck fractures, both FNS and CS combined with a medial plate are effective. Trial registration ChiCTR2100042960, registered 1 February 2021, http://www.chictr.org.cn .https://doi.org/10.1186/s13018-025-05972-0Femoral neck fracturesFemoral neck systemBone screwsMedial plateRandomized controlled trial
spellingShingle Mingyu Wen
Shengying Wang
Lihua Wang
Yuhai Wang
Shiyou Dai
Wen Liu
Xiao Fan
Femoral neck system versus cannulated screws combined with medial plate for femoral neck fractures in young and middle-aged patients: a prospective multicenter randomized controlled trial
Journal of Orthopaedic Surgery and Research
Femoral neck fractures
Femoral neck system
Bone screws
Medial plate
Randomized controlled trial
title Femoral neck system versus cannulated screws combined with medial plate for femoral neck fractures in young and middle-aged patients: a prospective multicenter randomized controlled trial
title_full Femoral neck system versus cannulated screws combined with medial plate for femoral neck fractures in young and middle-aged patients: a prospective multicenter randomized controlled trial
title_fullStr Femoral neck system versus cannulated screws combined with medial plate for femoral neck fractures in young and middle-aged patients: a prospective multicenter randomized controlled trial
title_full_unstemmed Femoral neck system versus cannulated screws combined with medial plate for femoral neck fractures in young and middle-aged patients: a prospective multicenter randomized controlled trial
title_short Femoral neck system versus cannulated screws combined with medial plate for femoral neck fractures in young and middle-aged patients: a prospective multicenter randomized controlled trial
title_sort femoral neck system versus cannulated screws combined with medial plate for femoral neck fractures in young and middle aged patients a prospective multicenter randomized controlled trial
topic Femoral neck fractures
Femoral neck system
Bone screws
Medial plate
Randomized controlled trial
url https://doi.org/10.1186/s13018-025-05972-0
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