Transforming organic chemistry research paradigms: Moving from manual efforts to the intersection of automation and artificial intelligence

Organic chemistry is undergoing a major paradigm shift, moving from a labor-intensive approach to a new era dominated by automation and artificial intelligence (AI). This transformative shift is being driven by technological advances, the ever-increasing demand for greater research efficiency and ac...

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Main Authors: Liu Chengchun, Chen Yuntian, Mo Fanyang
Format: Article
Language:English
Published: Science Press 2023-11-01
Series:National Science Open
Subjects:
Online Access:https://www.sciengine.com/doi/10.1360/nso/20230037
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author Liu Chengchun
Chen Yuntian
Mo Fanyang
author_facet Liu Chengchun
Chen Yuntian
Mo Fanyang
author_sort Liu Chengchun
collection DOAJ
description Organic chemistry is undergoing a major paradigm shift, moving from a labor-intensive approach to a new era dominated by automation and artificial intelligence (AI). This transformative shift is being driven by technological advances, the ever-increasing demand for greater research efficiency and accuracy, and the burgeoning growth of interdisciplinary research. AI models, supported by computational power and algorithms, are drastically reshaping synthetic planning and introducing groundbreaking ways to tackle complex molecular synthesis. In addition, autonomous robotic systems are rapidly accelerating the pace of discovery by performing tedious tasks with unprecedented speed and precision. This article examines the multiple opportunities and challenges presented by this paradigm shift and explores its far-reaching implications. It provides valuable insights into the future trajectory of organic chemistry research, which is increasingly defined by the synergistic interaction of automation and AI.
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spelling doaj-art-4338689c44bc4d93aa78bcc0968ac88a2025-08-20T02:02:04ZengScience PressNational Science Open2097-11682023-11-01310.1360/nso/20230037eb33e642Transforming organic chemistry research paradigms: Moving from manual efforts to the intersection of automation and artificial intelligenceLiu Chengchun0Chen Yuntian1Mo Fanyang2["School of Materials Science and Engineering, Peking University, Beijing 100871, China"]["Ningbo Institute of Digital Twin, Eastern Institute of Technology, Ningbo 315000, China"]["School of Materials Science and Engineering, Peking University, Beijing 100871, China","AI for Science (AI4S)-Preferred Program, Peking University Shenzhen Graduate School, Shenzhen 518055, China"]Organic chemistry is undergoing a major paradigm shift, moving from a labor-intensive approach to a new era dominated by automation and artificial intelligence (AI). This transformative shift is being driven by technological advances, the ever-increasing demand for greater research efficiency and accuracy, and the burgeoning growth of interdisciplinary research. AI models, supported by computational power and algorithms, are drastically reshaping synthetic planning and introducing groundbreaking ways to tackle complex molecular synthesis. In addition, autonomous robotic systems are rapidly accelerating the pace of discovery by performing tedious tasks with unprecedented speed and precision. This article examines the multiple opportunities and challenges presented by this paradigm shift and explores its far-reaching implications. It provides valuable insights into the future trajectory of organic chemistry research, which is increasingly defined by the synergistic interaction of automation and AI.https://www.sciengine.com/doi/10.1360/nso/20230037organic chemistryautomation platformartificial intelligencealgorithms
spellingShingle Liu Chengchun
Chen Yuntian
Mo Fanyang
Transforming organic chemistry research paradigms: Moving from manual efforts to the intersection of automation and artificial intelligence
National Science Open
organic chemistry
automation platform
artificial intelligence
algorithms
title Transforming organic chemistry research paradigms: Moving from manual efforts to the intersection of automation and artificial intelligence
title_full Transforming organic chemistry research paradigms: Moving from manual efforts to the intersection of automation and artificial intelligence
title_fullStr Transforming organic chemistry research paradigms: Moving from manual efforts to the intersection of automation and artificial intelligence
title_full_unstemmed Transforming organic chemistry research paradigms: Moving from manual efforts to the intersection of automation and artificial intelligence
title_short Transforming organic chemistry research paradigms: Moving from manual efforts to the intersection of automation and artificial intelligence
title_sort transforming organic chemistry research paradigms moving from manual efforts to the intersection of automation and artificial intelligence
topic organic chemistry
automation platform
artificial intelligence
algorithms
url https://www.sciengine.com/doi/10.1360/nso/20230037
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AT chenyuntian transformingorganicchemistryresearchparadigmsmovingfrommanualeffortstotheintersectionofautomationandartificialintelligence
AT mofanyang transformingorganicchemistryresearchparadigmsmovingfrommanualeffortstotheintersectionofautomationandartificialintelligence