The mechanism of telomerase Cajal body protein 1 regulating senescence of mouse bone marrow mesenchymal stem cells

The mechanism of telomerase Cajal body protein 1 regulating senescence of mouse bone marrow mesenchymal stem cells

Abstract Objective The regulatory ability of bone marrow stem cells (BMSC) to chemokines and inflammatory factors has a significant effect in a variety of diseases. It is very important to delay the aging of BMSC and restore the function of aging BMSC. Methods Mouse BMSC was prepared and identified....

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Bibliographic Details
Main Authors: Shu-qian Lin, Nini Tian, Xiang Yao, Xing-hua Pan, Zi-an Li, Qiang Wang, Jin Gao, Xi-long Zhao, Guang-ping Ruan
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Stem Cell Research & Therapy
Subjects:
Bone marrow mesenchymal stem cells
Aging gene
Telomerase Cajal body protein 1
Aging protein
Cell transcriptome sequencing
Online Access:https://doi.org/10.1186/s13287-025-04406-2
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