Racial segregation and genomics-related knowledge, self-efficacy, perceived importance, and communication among medically underserved patients

Purpose: There is limited research on the relationship between structural environmental factors and genomics-related knowledge, self-efficacy, perceived importance, and communication. We examined the potential impact of racial segregation on these genomics-related outcomes among medically underserve...

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Main Authors: Jemar R. Bather, Melody S. Goodman, Kimberly A. Kaphingst
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Genetics in Medicine Open
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Online Access:http://www.sciencedirect.com/science/article/pii/S2949774423008531
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author Jemar R. Bather
Melody S. Goodman
Kimberly A. Kaphingst
author_facet Jemar R. Bather
Melody S. Goodman
Kimberly A. Kaphingst
author_sort Jemar R. Bather
collection DOAJ
description Purpose: There is limited research on the relationship between structural environmental factors and genomics-related knowledge, self-efficacy, perceived importance, and communication. We examined the potential impact of racial segregation on these genomics-related outcomes among medically underserved patients. Methods: We analyzed data from a sample of 546 patients recruited from a primary care clinic in St. Louis, Missouri. Multivariable models were used to examine associations between racial composition of social environments across the life course and genomics-related knowledge, self-efficacy, perceived importance, and communication. Results: Non-Hispanic White patients reporting multiple past White social environments had higher genetic knowledge than non-Hispanic White patients reporting one or no past White social environments (P = .021), Black patients reporting 1 or no past White social environments (P = .002), and Black patients reporting multiple past White social environments (P < .001). We also found that among those reporting multiple current White social environments, Black patients were more likely than non-Hispanic White patients to frequently communicate about family history with family (P = .003). Conclusion: These findings indicate that structural factors may affect understanding of genetic information and communication about family history among medically underserved patients. Targeted interventions may increase the use of genetic services among this population and reduce health inequities.
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spelling doaj-art-4316eb910bce4585ab722938be3bc59c2025-08-20T02:18:29ZengElsevierGenetics in Medicine Open2949-77442024-01-01210084410.1016/j.gimo.2023.100844Racial segregation and genomics-related knowledge, self-efficacy, perceived importance, and communication among medically underserved patientsJemar R. Bather0Melody S. Goodman1Kimberly A. Kaphingst2Department of Biostatistics, New York University School of Global Public Health, New York, NY; Center for Anti-racism, Social Justice, &amp; Public Health, New York University School of Global Public Health, New York, NY; Correspondence and requests for materials should be addressed to Jemar R. Bather, Department of Biostatistics, New York University School of Global Public Health, 708 Broadway, 7th Floor, New York, NY 10003.Department of Biostatistics, New York University School of Global Public Health, New York, NY; Center for Anti-racism, Social Justice, &amp; Public Health, New York University School of Global Public Health, New York, NYHuntsman Cancer Institute, University of Utah, Salt Lake City, UT; Department of Communication, University of Utah, Salt Lake City, UTPurpose: There is limited research on the relationship between structural environmental factors and genomics-related knowledge, self-efficacy, perceived importance, and communication. We examined the potential impact of racial segregation on these genomics-related outcomes among medically underserved patients. Methods: We analyzed data from a sample of 546 patients recruited from a primary care clinic in St. Louis, Missouri. Multivariable models were used to examine associations between racial composition of social environments across the life course and genomics-related knowledge, self-efficacy, perceived importance, and communication. Results: Non-Hispanic White patients reporting multiple past White social environments had higher genetic knowledge than non-Hispanic White patients reporting one or no past White social environments (P = .021), Black patients reporting 1 or no past White social environments (P = .002), and Black patients reporting multiple past White social environments (P < .001). We also found that among those reporting multiple current White social environments, Black patients were more likely than non-Hispanic White patients to frequently communicate about family history with family (P = .003). Conclusion: These findings indicate that structural factors may affect understanding of genetic information and communication about family history among medically underserved patients. Targeted interventions may increase the use of genetic services among this population and reduce health inequities.http://www.sciencedirect.com/science/article/pii/S2949774423008531Residential segregationFamily health historyGenetic servicesGenetic testingRacial and ethnic minorities
spellingShingle Jemar R. Bather
Melody S. Goodman
Kimberly A. Kaphingst
Racial segregation and genomics-related knowledge, self-efficacy, perceived importance, and communication among medically underserved patients
Genetics in Medicine Open
Residential segregation
Family health history
Genetic services
Genetic testing
Racial and ethnic minorities
title Racial segregation and genomics-related knowledge, self-efficacy, perceived importance, and communication among medically underserved patients
title_full Racial segregation and genomics-related knowledge, self-efficacy, perceived importance, and communication among medically underserved patients
title_fullStr Racial segregation and genomics-related knowledge, self-efficacy, perceived importance, and communication among medically underserved patients
title_full_unstemmed Racial segregation and genomics-related knowledge, self-efficacy, perceived importance, and communication among medically underserved patients
title_short Racial segregation and genomics-related knowledge, self-efficacy, perceived importance, and communication among medically underserved patients
title_sort racial segregation and genomics related knowledge self efficacy perceived importance and communication among medically underserved patients
topic Residential segregation
Family health history
Genetic services
Genetic testing
Racial and ethnic minorities
url http://www.sciencedirect.com/science/article/pii/S2949774423008531
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