NK cell-specific knockout of UTX modulates pulmonary metastasis of melanoma in a sex-dependent manner

NK cell-specific knockout of UTX modulates pulmonary metastasis of melanoma in a sex-dependent manner

Objective‍　‍To explore the role of X chromosome encoded epigenetic regulator UTX in NK cell-mediated anti-tumor activity. Methods‍　‍Male Ncr1-iCre mice were crossed with female UTXfl/fl mice to generate F1 Ncr1-iCre+UTXfl/- male mice, which were further crossed with female UTXfl/fl mice to obtain ma...

Full description

Saved in:
Bibliographic Details
Main Authors: HUANG Pei, WANG Hongchen, HUANG He
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2025-04-01
Series:陆军军医大学学报
Subjects:
‍pulmonary metastasis
melanoma
nk cells
sex
utx
Online Access:https://aammt.tmmu.edu.cn/html/202411078.html
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items