Lifespan reference curves for harmonizing multi-site regional brain white matter metrics from diffusion MRI

Abstract Age-related white matter (WM) microstructure maturation and decline occur throughout the human lifespan, complementing the process of gray matter development and degeneration. Here, we create normative lifespan reference curves for global and regional WM microstructure by harmonizing diffus...

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Main Authors: Alyssa H. Zhu, Talia M. Nir, Shayan Javid, Julio E. Villalón-Reina, Amanda L. Rodrigue, Lachlan T. Strike, Greig I. de Zubicaray, Katie L. McMahon, Margaret J. Wright, Sarah E. Medland, John Blangero, David C. Glahn, Peter Kochunov, Douglas E. Williamson, Asta K. Håberg, Paul M. Thompson, Neda Jahanshad
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-025-05028-2
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