Clinical and Radiological Longitudinal 3-month Prospective Follow-up of Patients with Dengue-associated Longitudinally Extensive Transverse Myelitis

Dengue is a vector-borne tropical disease. It usually presents as dengue fever, dengue hemorrhagic fever, or dengue shock syndrome. Neurologic manifestations of dengue are rare but not uncommon. They can present as encephalitis, acute disseminated encephalomyelitis, transverse myelitis, cranial nerv...

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Main Authors: Haramohan Sahoo, Gaurav Sharma, Ankit Patel, Manaswini Reddy Konkeesa, Bhupesh Goyal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Journal of Applied Sciences and Clinical Practice
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Online Access:https://journals.lww.com/10.4103/jascp.jascp_34_24
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Summary:Dengue is a vector-borne tropical disease. It usually presents as dengue fever, dengue hemorrhagic fever, or dengue shock syndrome. Neurologic manifestations of dengue are rare but not uncommon. They can present as encephalitis, acute disseminated encephalomyelitis, transverse myelitis, cranial nerve palsy, and Guillain–Barré syndrome. Longitudinally extensive transverse myelitis (LETM) can be seen as a complication of dengue fever (para-infectious) or after the fever has subsided (postinfectious). We followed up the postdengue LETM patients who presented to our hospital in the whole of the year 2023, clinically and radiologically, over 3 months. We found that these patients had a major disability in their lower limbs, and it resolved gradually with medication and physiotherapy over 3 months. The radiological resolution of the spinal cord changes was also significant. The long-term oral steroid had no better outcome than short-term pulse high-dose steroid therapy.
ISSN:2772-364X
2772-3658