Acetylated KIAA1429 by TIP60 facilitates metastasis and immune evasion of hepatocellular carcinoma via N6-methyladenosine-KDM5B-mediated regulation of FoxO1
Abstract Hepatocellular carcinoma (HCC) is characterized by programmed cell death ligand-1 (PD-L1)-mediated immune escape. This study aimed to elucidate the function and mechanism behind KIAA1429, a component of N6-methyladenosine (m6A) complex, in immune escape of HCC. PD-L1 expression was assessed...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-04-01
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| Series: | Cell Death Discovery |
| Online Access: | https://doi.org/10.1038/s41420-025-02462-4 |
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