Cashmere cyclic growth affected by different photoperiods alters DNA methylation patterns
Whole-genome bisulfite sequencing was used to study epigenetic differences in hair follicles from Inner Mongolia Albas cashmere goats during long and short photoperiods. Results showed earlier anagen entry in short photoperiod. Genome-wide cytosine methylation was 3.23%, with CG, CHG, and CHH methyl...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | All Life |
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| Online Access: | http://dx.doi.org/10.1080/26895293.2024.2393847 |
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| author | Ruoyang Zhao Tiecheng Wu Jun Yin Tao Wang Yunmei He Yahan Wu Yulin Gao Bin Liu |
| author_facet | Ruoyang Zhao Tiecheng Wu Jun Yin Tao Wang Yunmei He Yahan Wu Yulin Gao Bin Liu |
| author_sort | Ruoyang Zhao |
| collection | DOAJ |
| description | Whole-genome bisulfite sequencing was used to study epigenetic differences in hair follicles from Inner Mongolia Albas cashmere goats during long and short photoperiods. Results showed earlier anagen entry in short photoperiod. Genome-wide cytosine methylation was 3.23%, with CG, CHG, and CHH methylation rates at 48.00%, 0.19%, and 0.17%, respectively. Methylation was higher for CG than for CHG and CHH, and higher for introns than exons and downstream regions. Both groups had similar levels of CG, CHG, and CHH methylation, but CHH methylation levels differed slightly between photoperiods. A total of 9,700 differentially methylated regions (DMRs) and 4,187 genes (DMGs) were identified. Gene Ontology (GO) and KEGG analyses revealed significant enrichment in 67 GO terms and 41 signaling pathways related to circadian rhythms, bringing new insights in the role of DNA methylation in cashmere growth and development. |
| format | Article |
| id | doaj-art-42d95b683f0f4e45941467c7e3e8d1b0 |
| institution | Kabale University |
| issn | 2689-5307 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | All Life |
| spelling | doaj-art-42d95b683f0f4e45941467c7e3e8d1b02025-01-20T14:38:00ZengTaylor & Francis GroupAll Life2689-53072024-12-01170110.1080/26895293.2024.23938472393847Cashmere cyclic growth affected by different photoperiods alters DNA methylation patternsRuoyang Zhao0Tiecheng Wu1Jun Yin2Tao Wang3Yunmei He4Yahan Wu5Yulin Gao6Bin Liu7Institute of Animal HusbandryInstitute of Animal HusbandryInner Mongolia Agricultural UniversityInstitute of Animal HusbandryEtoke Banner Agricultural and Animal Husbandry Technology Popularization CenterEtuokeqianqi Arctic God Research Institute of Cashmere and LivestockInstitute of Animal HusbandryInstitute of Animal HusbandryWhole-genome bisulfite sequencing was used to study epigenetic differences in hair follicles from Inner Mongolia Albas cashmere goats during long and short photoperiods. Results showed earlier anagen entry in short photoperiod. Genome-wide cytosine methylation was 3.23%, with CG, CHG, and CHH methylation rates at 48.00%, 0.19%, and 0.17%, respectively. Methylation was higher for CG than for CHG and CHH, and higher for introns than exons and downstream regions. Both groups had similar levels of CG, CHG, and CHH methylation, but CHH methylation levels differed slightly between photoperiods. A total of 9,700 differentially methylated regions (DMRs) and 4,187 genes (DMGs) were identified. Gene Ontology (GO) and KEGG analyses revealed significant enrichment in 67 GO terms and 41 signaling pathways related to circadian rhythms, bringing new insights in the role of DNA methylation in cashmere growth and development.http://dx.doi.org/10.1080/26895293.2024.2393847goat cashmerehair follicledna methylationsequencingdmrslight duration |
| spellingShingle | Ruoyang Zhao Tiecheng Wu Jun Yin Tao Wang Yunmei He Yahan Wu Yulin Gao Bin Liu Cashmere cyclic growth affected by different photoperiods alters DNA methylation patterns All Life goat cashmere hair follicle dna methylation sequencing dmrs light duration |
| title | Cashmere cyclic growth affected by different photoperiods alters DNA methylation patterns |
| title_full | Cashmere cyclic growth affected by different photoperiods alters DNA methylation patterns |
| title_fullStr | Cashmere cyclic growth affected by different photoperiods alters DNA methylation patterns |
| title_full_unstemmed | Cashmere cyclic growth affected by different photoperiods alters DNA methylation patterns |
| title_short | Cashmere cyclic growth affected by different photoperiods alters DNA methylation patterns |
| title_sort | cashmere cyclic growth affected by different photoperiods alters dna methylation patterns |
| topic | goat cashmere hair follicle dna methylation sequencing dmrs light duration |
| url | http://dx.doi.org/10.1080/26895293.2024.2393847 |
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