Unilateral juvenile (virginal) hypertrophy of the breast

Juvenile hypertrophy of the breast (JHB) is an uncommon, benign disorder and typically occurs in peri-pubertal females. The etiology ofJHB is uncertain. It may represent an end-organ hypersensitivity of the breast to normal levels of sex steroids. Clinically, it is characterized by rapid enla...

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Main Authors: Dilek Güneş, Kamer Mutafoğlu-Uysal, Tülay Canda, Serdar Saydam, Ayşe Pinar Cemeroğlu, Nur Olgun
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2008-06-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/2429
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author Dilek Güneş
Kamer Mutafoğlu-Uysal
Tülay Canda
Serdar Saydam
Ayşe Pinar Cemeroğlu
Nur Olgun
author_facet Dilek Güneş
Kamer Mutafoğlu-Uysal
Tülay Canda
Serdar Saydam
Ayşe Pinar Cemeroğlu
Nur Olgun
author_sort Dilek Güneş
collection DOAJ
description Juvenile hypertrophy of the breast (JHB) is an uncommon, benign disorder and typically occurs in peri-pubertal females. The etiology ofJHB is uncertain. It may represent an end-organ hypersensitivity of the breast to normal levels of sex steroids. Clinically, it is characterized by rapid enlargement of breasts, either unilateral or bilateral. The definitive diagnosis is made by histopathologic examination. Treatment recommendations include surgery and hormonal therapy, although hormonal manipulation is still controversial in pediatric patients. Here we report a 13-year-old girl with unilateral JHB who did not require surgery or medical treatment.
format Article
id doaj-art-42c8086979be4fe893074b7bd5d0f25f
institution OA Journals
issn 0041-4301
2791-6421
language English
publishDate 2008-06-01
publisher Hacettepe University Institute of Child Health
record_format Article
series The Turkish Journal of Pediatrics
spelling doaj-art-42c8086979be4fe893074b7bd5d0f25f2025-08-20T02:01:53ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212008-06-01503Unilateral juvenile (virginal) hypertrophy of the breastDilek Güneş0Kamer Mutafoğlu-UysalTülay CandaSerdar SaydamAyşe Pinar CemeroğluNur OlgunDepartment of Pediatric Oncology, Dokuz Eylül University Institute of Oncology, Izmir, Turkey. Juvenile hypertrophy of the breast (JHB) is an uncommon, benign disorder and typically occurs in peri-pubertal females. The etiology ofJHB is uncertain. It may represent an end-organ hypersensitivity of the breast to normal levels of sex steroids. Clinically, it is characterized by rapid enlargement of breasts, either unilateral or bilateral. The definitive diagnosis is made by histopathologic examination. Treatment recommendations include surgery and hormonal therapy, although hormonal manipulation is still controversial in pediatric patients. Here we report a 13-year-old girl with unilateral JHB who did not require surgery or medical treatment. https://turkjpediatr.org/article/view/2429
spellingShingle Dilek Güneş
Kamer Mutafoğlu-Uysal
Tülay Canda
Serdar Saydam
Ayşe Pinar Cemeroğlu
Nur Olgun
Unilateral juvenile (virginal) hypertrophy of the breast
The Turkish Journal of Pediatrics
title Unilateral juvenile (virginal) hypertrophy of the breast
title_full Unilateral juvenile (virginal) hypertrophy of the breast
title_fullStr Unilateral juvenile (virginal) hypertrophy of the breast
title_full_unstemmed Unilateral juvenile (virginal) hypertrophy of the breast
title_short Unilateral juvenile (virginal) hypertrophy of the breast
title_sort unilateral juvenile virginal hypertrophy of the breast
url https://turkjpediatr.org/article/view/2429
work_keys_str_mv AT dilekgunes unilateraljuvenilevirginalhypertrophyofthebreast
AT kamermutafogluuysal unilateraljuvenilevirginalhypertrophyofthebreast
AT tulaycanda unilateraljuvenilevirginalhypertrophyofthebreast
AT serdarsaydam unilateraljuvenilevirginalhypertrophyofthebreast
AT aysepinarcemeroglu unilateraljuvenilevirginalhypertrophyofthebreast
AT nurolgun unilateraljuvenilevirginalhypertrophyofthebreast