Unveiling the dynamic trends of plant-derived exosome nanovesicles-based theranostics: through bibliometric and visualized analysis
Plant-derived exosome nanovesicles (PDENs) have emerged as eco-friendly, sustainable and highly efficient platforms for drug delivery, attracting significant attention in biomedical research. As a consequence, PDENs have become a focus for multidisciplinary investigation. Despite extensive research,...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-06-01
|
| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1553915/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850166372202446848 |
|---|---|
| author | Siyang Cao Siyang Cao Yingchen Pang Yingchen Pang Yihao Wei Yihao Wei Yihao Wei Deli Wang Deli Wang Ao Xiong Ao Xiong Jun Yang Hui Zeng Hui Zeng |
| author_facet | Siyang Cao Siyang Cao Yingchen Pang Yingchen Pang Yihao Wei Yihao Wei Yihao Wei Deli Wang Deli Wang Ao Xiong Ao Xiong Jun Yang Hui Zeng Hui Zeng |
| author_sort | Siyang Cao |
| collection | DOAJ |
| description | Plant-derived exosome nanovesicles (PDENs) have emerged as eco-friendly, sustainable and highly efficient platforms for drug delivery, attracting significant attention in biomedical research. As a consequence, PDENs have become a focus for multidisciplinary investigation. Despite extensive research, impartial and comprehensive evaluations of PDENs-based theranostic applications remain scarce. This study fills this gap by using bibliometric techniques to systematically analyze 15 years of scientific publications. The analysis is based on data retrieved from the Web of Science Core Collection, covering studies published from 2009 to 2024. Advanced bibliometric tools and visualization techniques were utilized to ensure a rigorous and detailed analysis. The results highlight China’s dominant position, contributing 35.09% of all publications, thereby significantly influencing the research trajectory in this field. Key contributions have been made by institutions such as the Nanjing University of Chinese Medicine, the Chinese Academy of Sciences and Zhejiang University, with Stefania Raimondo emerging as the most productive researcher. International Journal of Molecular Sciences stands out as the journal with the largest number of publications in this area. The study also identifies key related diseases, including colonic diseases, vascular diseases, osteosarcoma and DNA virus infections, etc. In conclusion, this study offers a detailed assessment of advancements and evolving patterns in PDENs-based theranostics over the past 15 years. It emphasizes critical areas that require further focus and systematic exploration by the scientific community. Additionally, this analysis identifies major research hotspots and emerging boundaries, providing scholars and research institutions with strategic insights to shape future studies. |
| format | Article |
| id | doaj-art-42bc3c685fd4470da18b6d8d9f08c96a |
| institution | OA Journals |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-42bc3c685fd4470da18b6d8d9f08c96a2025-08-20T02:21:29ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-06-011210.3389/fmed.2025.15539151553915Unveiling the dynamic trends of plant-derived exosome nanovesicles-based theranostics: through bibliometric and visualized analysisSiyang Cao0Siyang Cao1Yingchen Pang2Yingchen Pang3Yihao Wei4Yihao Wei5Yihao Wei6Deli Wang7Deli Wang8Ao Xiong9Ao Xiong10Jun Yang11Hui Zeng12Hui Zeng13Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen, Shenzhen, Guangdong, ChinaShenzhen Key Laboratory of Orthopaedic Diseases and Biomaterials Research, Peking University Shenzhen Hospita, Shenzhen, Guangdong, ChinaDepartment of Pulmonary and Critical Care Medicine, Peking University Shenzhen Hospital, Shenzhen, Guangdong, ChinaDepartment of Pulmonary and Critical Care Medicine, Shenzhen Xinhua Hospital, Shenzhen, Guangdong, ChinaDepartment of Rehabilitation Science, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region, Hong Kong, ChinaFaculty of Pharmaceutical Sciences, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences (CAS), Shenzhen, Guangdong, ChinaFaculty of Pharmaceutical Sciences, Shenzhen University of Advanced Technology, Shenzhen, Guangdong, ChinaDepartment of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen, Shenzhen, Guangdong, ChinaShenzhen Key Laboratory of Orthopaedic Diseases and Biomaterials Research, Peking University Shenzhen Hospita, Shenzhen, Guangdong, ChinaDepartment of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen, Shenzhen, Guangdong, ChinaShenzhen Key Laboratory of Orthopaedic Diseases and Biomaterials Research, Peking University Shenzhen Hospita, Shenzhen, Guangdong, ChinaDepartment of Radiology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, ChinaShenzhen Key Laboratory of Orthopaedic Diseases and Biomaterials Research, Peking University Shenzhen Hospita, Shenzhen, Guangdong, ChinaDepartment of Orthopedics, Shenzhen Second People’s Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong, ChinaPlant-derived exosome nanovesicles (PDENs) have emerged as eco-friendly, sustainable and highly efficient platforms for drug delivery, attracting significant attention in biomedical research. As a consequence, PDENs have become a focus for multidisciplinary investigation. Despite extensive research, impartial and comprehensive evaluations of PDENs-based theranostic applications remain scarce. This study fills this gap by using bibliometric techniques to systematically analyze 15 years of scientific publications. The analysis is based on data retrieved from the Web of Science Core Collection, covering studies published from 2009 to 2024. Advanced bibliometric tools and visualization techniques were utilized to ensure a rigorous and detailed analysis. The results highlight China’s dominant position, contributing 35.09% of all publications, thereby significantly influencing the research trajectory in this field. Key contributions have been made by institutions such as the Nanjing University of Chinese Medicine, the Chinese Academy of Sciences and Zhejiang University, with Stefania Raimondo emerging as the most productive researcher. International Journal of Molecular Sciences stands out as the journal with the largest number of publications in this area. The study also identifies key related diseases, including colonic diseases, vascular diseases, osteosarcoma and DNA virus infections, etc. In conclusion, this study offers a detailed assessment of advancements and evolving patterns in PDENs-based theranostics over the past 15 years. It emphasizes critical areas that require further focus and systematic exploration by the scientific community. Additionally, this analysis identifies major research hotspots and emerging boundaries, providing scholars and research institutions with strategic insights to shape future studies.https://www.frontiersin.org/articles/10.3389/fmed.2025.1553915/fullplant-derived exosome-like nanoparticlesbiotherapeutic applicationsdelivery strategybibliometricsvisualized analysistheranostics |
| spellingShingle | Siyang Cao Siyang Cao Yingchen Pang Yingchen Pang Yihao Wei Yihao Wei Yihao Wei Deli Wang Deli Wang Ao Xiong Ao Xiong Jun Yang Hui Zeng Hui Zeng Unveiling the dynamic trends of plant-derived exosome nanovesicles-based theranostics: through bibliometric and visualized analysis Frontiers in Medicine plant-derived exosome-like nanoparticles biotherapeutic applications delivery strategy bibliometrics visualized analysis theranostics |
| title | Unveiling the dynamic trends of plant-derived exosome nanovesicles-based theranostics: through bibliometric and visualized analysis |
| title_full | Unveiling the dynamic trends of plant-derived exosome nanovesicles-based theranostics: through bibliometric and visualized analysis |
| title_fullStr | Unveiling the dynamic trends of plant-derived exosome nanovesicles-based theranostics: through bibliometric and visualized analysis |
| title_full_unstemmed | Unveiling the dynamic trends of plant-derived exosome nanovesicles-based theranostics: through bibliometric and visualized analysis |
| title_short | Unveiling the dynamic trends of plant-derived exosome nanovesicles-based theranostics: through bibliometric and visualized analysis |
| title_sort | unveiling the dynamic trends of plant derived exosome nanovesicles based theranostics through bibliometric and visualized analysis |
| topic | plant-derived exosome-like nanoparticles biotherapeutic applications delivery strategy bibliometrics visualized analysis theranostics |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2025.1553915/full |
| work_keys_str_mv | AT siyangcao unveilingthedynamictrendsofplantderivedexosomenanovesiclesbasedtheranosticsthroughbibliometricandvisualizedanalysis AT siyangcao unveilingthedynamictrendsofplantderivedexosomenanovesiclesbasedtheranosticsthroughbibliometricandvisualizedanalysis AT yingchenpang unveilingthedynamictrendsofplantderivedexosomenanovesiclesbasedtheranosticsthroughbibliometricandvisualizedanalysis AT yingchenpang unveilingthedynamictrendsofplantderivedexosomenanovesiclesbasedtheranosticsthroughbibliometricandvisualizedanalysis AT yihaowei unveilingthedynamictrendsofplantderivedexosomenanovesiclesbasedtheranosticsthroughbibliometricandvisualizedanalysis AT yihaowei unveilingthedynamictrendsofplantderivedexosomenanovesiclesbasedtheranosticsthroughbibliometricandvisualizedanalysis AT yihaowei unveilingthedynamictrendsofplantderivedexosomenanovesiclesbasedtheranosticsthroughbibliometricandvisualizedanalysis AT deliwang unveilingthedynamictrendsofplantderivedexosomenanovesiclesbasedtheranosticsthroughbibliometricandvisualizedanalysis AT deliwang unveilingthedynamictrendsofplantderivedexosomenanovesiclesbasedtheranosticsthroughbibliometricandvisualizedanalysis AT aoxiong unveilingthedynamictrendsofplantderivedexosomenanovesiclesbasedtheranosticsthroughbibliometricandvisualizedanalysis AT aoxiong unveilingthedynamictrendsofplantderivedexosomenanovesiclesbasedtheranosticsthroughbibliometricandvisualizedanalysis AT junyang unveilingthedynamictrendsofplantderivedexosomenanovesiclesbasedtheranosticsthroughbibliometricandvisualizedanalysis AT huizeng unveilingthedynamictrendsofplantderivedexosomenanovesiclesbasedtheranosticsthroughbibliometricandvisualizedanalysis AT huizeng unveilingthedynamictrendsofplantderivedexosomenanovesiclesbasedtheranosticsthroughbibliometricandvisualizedanalysis |