Weight-based tranexamic acid lowers the risk of postoperative blood loss and transfusion requirements compared with fixed-dose regimen in revision knee arthroplasty: a comparative study

Weight-based tranexamic acid lowers the risk of postoperative blood loss and transfusion requirements compared with fixed-dose regimen in revision knee arthroplasty: a comparative study

Abstract Background Intravenous tranexamic acid (TXA) dosing regimens differ substantially across studies, varying from fixed doses (e.g., 1–2 g) to weight-based protocols (e.g., 10–20 mg/kg). This study aimed to compare postoperative blood loss, transfusion rates, in-hospital mortality, and complic...

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Bibliographic Details
Main Authors: Chenchen Yang, Baochao Ji, Guoqing Li, Xiaogang Zhang, Boyong Xu, Askar Maimaitiming, Li Cao
Format: Article
Language:English
Published: SpringerOpen 2025-05-01
Series:Journal of Orthopaedics and Traumatology
Subjects:
Tranexamic acid
Revision total knee arthroplasty
Blood loss
Transfusion
Online Access:https://doi.org/10.1186/s10195-025-00844-z
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