Weizmannia coagulans BC99 alleviates hyperuricemia and oxidative stress via DAF-16/SKN-1 activation in Caenorhabditis elegan

Weizmannia coagulans BC99 alleviates hyperuricemia and oxidative stress via DAF-16/SKN-1 activation in Caenorhabditis elegan

IntroductionHyperuricemia (HUA) refers to the presence of excess uric acid (UA) in the blood, which increases the risk of chronic kidney disease and gout. Probiotics have the potential to alleviate HUA.MethodsThis study established a hyperuricemia model using Caenorhabditis elegans (C. elegans), and...

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Bibliographic Details
Main Authors: Yinyin Gao, Cheng Li, Junfei Li, Mengyao Duan, Xuan Li, Lina Zhao, Ying Wu, Shaobin Gu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Microbiology
Subjects:
Weizmannella coagulans
Caenorhabditis elegans
hyperuricemia
metabolomics
mechanism
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1498540/full
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