T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease
Aim of the study was to investigate the levels of individual subpopulations of T-regulatory (T-reg) cells in patients with different phenotypes of chronic obstructive pulmonary disease (COPD) with moderate bronchial asthma and healthy volunteers. COPD was associated with increased level of natural (...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2011-02-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/1314 |
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| author | N. A. Kirillova I. A. Deyev Ye. E. Kremer L. M. Ogorodova G. E. Chernogoryuk |
| author_facet | N. A. Kirillova I. A. Deyev Ye. E. Kremer L. M. Ogorodova G. E. Chernogoryuk |
| author_sort | N. A. Kirillova |
| collection | DOAJ |
| description | Aim of the study was to investigate the levels of individual subpopulations of T-regulatory (T-reg) cells in patients with different phenotypes of chronic obstructive pulmonary disease (COPD) with moderate bronchial asthma and healthy volunteers. COPD was associated with increased level of natural (CD4+CD25high) T-cells, while emphysematous phenotype of disease was associated with the highest pool of natural CD4+CD25high. Bronchial asthma was associated with low levels of inducible (CD4+ FoxP3+ ) T-reg. |
| format | Article |
| id | doaj-art-42b28bc66af1422b933e672cb314acb2 |
| institution | DOAJ |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2011-02-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-42b28bc66af1422b933e672cb314acb22025-08-20T03:21:46ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842011-02-01101485410.20538/1682-0363-2011-1-48-54837T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary diseaseN. A. Kirillova0I. A. Deyev1Ye. E. Kremer2L. M. Ogorodova3G. E. Chernogoryuk4Сибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетAim of the study was to investigate the levels of individual subpopulations of T-regulatory (T-reg) cells in patients with different phenotypes of chronic obstructive pulmonary disease (COPD) with moderate bronchial asthma and healthy volunteers. COPD was associated with increased level of natural (CD4+CD25high) T-cells, while emphysematous phenotype of disease was associated with the highest pool of natural CD4+CD25high. Bronchial asthma was associated with low levels of inducible (CD4+ FoxP3+ ) T-reg.https://bulletin.ssmu.ru/jour/article/view/1314chronic obstructive pulmonary diseasebronchial asthmacopd phenotypest-regulatory cells |
| spellingShingle | N. A. Kirillova I. A. Deyev Ye. E. Kremer L. M. Ogorodova G. E. Chernogoryuk T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease Бюллетень сибирской медицины chronic obstructive pulmonary disease bronchial asthma copd phenotypes t-regulatory cells |
| title | T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease |
| title_full | T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease |
| title_fullStr | T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease |
| title_full_unstemmed | T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease |
| title_short | T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease |
| title_sort | t regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease |
| topic | chronic obstructive pulmonary disease bronchial asthma copd phenotypes t-regulatory cells |
| url | https://bulletin.ssmu.ru/jour/article/view/1314 |
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