T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease
Aim of the study was to investigate the levels of individual subpopulations of T-regulatory (T-reg) cells in patients with different phenotypes of chronic obstructive pulmonary disease (COPD) with moderate bronchial asthma and healthy volunteers. COPD was associated with increased level of natural (...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Siberian State Medical University (Tomsk)
2011-02-01
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| Series: | Бюллетень сибирской медицины |
| Subjects: | |
| Online Access: | https://bulletin.ssmu.ru/jour/article/view/1314 |
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| Summary: | Aim of the study was to investigate the levels of individual subpopulations of T-regulatory (T-reg) cells in patients with different phenotypes of chronic obstructive pulmonary disease (COPD) with moderate bronchial asthma and healthy volunteers. COPD was associated with increased level of natural (CD4+CD25high) T-cells, while emphysematous phenotype of disease was associated with the highest pool of natural CD4+CD25high. Bronchial asthma was associated with low levels of inducible (CD4+ FoxP3+ ) T-reg. |
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| ISSN: | 1682-0363 1819-3684 |