Multifocal electroretinogram evaluation of different optical coherence tomography patterns of diabetic macular edema
Purpose To correlate macular function to morphological patterns of diabetic macular edema (DME) observed by optical coherence tomography (OCT). Patients and methods This study included 100 DME eyes and 60 control eyes. OCT patterns of DME were divided into: Type 1: diffuse retinal thickening (DRT);...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Journal of the Egyptian Ophthalmological Society |
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| Online Access: | https://journals.lww.com/10.4103/ejos.ejos_40_24 |
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| author | Abdelrahman W.M. Mohamed Yehia M. Khairat Heba R. AttaAllah Amr A.M. Abdelrahman |
| author_facet | Abdelrahman W.M. Mohamed Yehia M. Khairat Heba R. AttaAllah Amr A.M. Abdelrahman |
| author_sort | Abdelrahman W.M. Mohamed |
| collection | DOAJ |
| description | Purpose
To correlate macular function to morphological patterns of diabetic macular edema (DME) observed by optical coherence tomography (OCT).
Patients and methods
This study included 100 DME eyes and 60 control eyes. OCT patterns of DME were divided into: Type 1: diffuse retinal thickening (DRT); Type 2: cystoid macular edema (CME); Type 3: neurosensory detachment (NSD); and Type 4: the combined type that was further subdivided into: Type 4a: DRT with CME, Type 4b: DRT with NSD, and Type 4c: CME with NSD. These types were correlated with LogMAR VA and P1 wave amplitude and implicit time of multifocal electroretinogram.
Results
In both central ring 1 and paracentral ring 2, P1 amplitude was significantly reduced in all types of DME compared with control group. P1 amplitude was highest in Type 1, and lowest in Type 4c compared with other DME types. P1 implicit time was significantly delayed in all types, and significantly delayed in Type 4c compared with Type 1.
Conclusion
DRT was the best type for macular function, CME was associated with decreased P1 wave amplitude in central macular ring, NSD was associated with decreased P1 wave amplitude in the paracentral macular ring, combined CME with NSD carried the poorest visual function. From a practical point of view, combining OCT and multifocal electroretinogram testing may offer a potent method to assess the degree of retinal injury. |
| format | Article |
| id | doaj-art-42ab8a219f3f472bbbf0e1c5be60a3e3 |
| institution | Kabale University |
| issn | 2090-0686 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of the Egyptian Ophthalmological Society |
| spelling | doaj-art-42ab8a219f3f472bbbf0e1c5be60a3e32025-02-08T05:26:49ZengWolters Kluwer Medknow PublicationsJournal of the Egyptian Ophthalmological Society2090-06862025-01-011181556110.4103/ejos.ejos_40_24Multifocal electroretinogram evaluation of different optical coherence tomography patterns of diabetic macular edemaAbdelrahman W.M. MohamedYehia M. KhairatHeba R. AttaAllahAmr A.M. AbdelrahmanPurpose To correlate macular function to morphological patterns of diabetic macular edema (DME) observed by optical coherence tomography (OCT). Patients and methods This study included 100 DME eyes and 60 control eyes. OCT patterns of DME were divided into: Type 1: diffuse retinal thickening (DRT); Type 2: cystoid macular edema (CME); Type 3: neurosensory detachment (NSD); and Type 4: the combined type that was further subdivided into: Type 4a: DRT with CME, Type 4b: DRT with NSD, and Type 4c: CME with NSD. These types were correlated with LogMAR VA and P1 wave amplitude and implicit time of multifocal electroretinogram. Results In both central ring 1 and paracentral ring 2, P1 amplitude was significantly reduced in all types of DME compared with control group. P1 amplitude was highest in Type 1, and lowest in Type 4c compared with other DME types. P1 implicit time was significantly delayed in all types, and significantly delayed in Type 4c compared with Type 1. Conclusion DRT was the best type for macular function, CME was associated with decreased P1 wave amplitude in central macular ring, NSD was associated with decreased P1 wave amplitude in the paracentral macular ring, combined CME with NSD carried the poorest visual function. From a practical point of view, combining OCT and multifocal electroretinogram testing may offer a potent method to assess the degree of retinal injury.https://journals.lww.com/10.4103/ejos.ejos_40_24diabetic macular edemamultifocal electroretinogramoptical coherence tomography |
| spellingShingle | Abdelrahman W.M. Mohamed Yehia M. Khairat Heba R. AttaAllah Amr A.M. Abdelrahman Multifocal electroretinogram evaluation of different optical coherence tomography patterns of diabetic macular edema Journal of the Egyptian Ophthalmological Society diabetic macular edema multifocal electroretinogram optical coherence tomography |
| title | Multifocal electroretinogram evaluation of different optical coherence tomography patterns of diabetic macular edema |
| title_full | Multifocal electroretinogram evaluation of different optical coherence tomography patterns of diabetic macular edema |
| title_fullStr | Multifocal electroretinogram evaluation of different optical coherence tomography patterns of diabetic macular edema |
| title_full_unstemmed | Multifocal electroretinogram evaluation of different optical coherence tomography patterns of diabetic macular edema |
| title_short | Multifocal electroretinogram evaluation of different optical coherence tomography patterns of diabetic macular edema |
| title_sort | multifocal electroretinogram evaluation of different optical coherence tomography patterns of diabetic macular edema |
| topic | diabetic macular edema multifocal electroretinogram optical coherence tomography |
| url | https://journals.lww.com/10.4103/ejos.ejos_40_24 |
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