Identifying the Intergenic ALK Fusion LOC388942‐ALK as a Driver of Non–Small Cell Lung Cancer

Identifying the Intergenic ALK Fusion LOC388942‐ALK as a Driver of Non–Small Cell Lung Cancer

ABSTRACT ALK fusions, such as the classic EML4‐ALK, are known drivers of lung cancer and effective therapeutic targets. However, variant ALK fusions, including intergenic fusions like LOC388942‐ALK (LA), have been detected in increasing numbers of patients, with their roles in tumorigenesis and ALK...

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Bibliographic Details
Main Authors: Xiaoqian Zhai, Manli Wang, Qi Zhang, Donglin Li, Yanmou Wu, ZuoYu Liang, Jiewei Liu, Weiya Wang, Yu Liu, Guowei Che, Qinghua Zhou, Chong Chen
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:MedComm
Subjects:
ALK fusion
FOS
intergenic fusion
non–small cell lung cancer
tumorigenesis
Online Access:https://doi.org/10.1002/mco2.70154
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