Time-of-day effect of high-intensity muscle contraction on mTOR signaling and protein synthesis in mice

Time-of-day effect of high-intensity muscle contraction on mTOR signaling and protein synthesis in mice

Abstract Resistance exercise promotes muscle protein synthesis by activating mechanistic target of rapamycin (mTOR). The magnitude of muscle hypertrophy might differ depending on the timing of resistance exercise, but the molecular mechanism remains unclear. We aimed to define whether the time of da...

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Bibliographic Details
Main Authors: Taiga Mishima, Yosuke Takenaka, Akiko Hashimoto-Hachiya, Yukiko Tanigawa, Natsumi Suzuki, Katsutaka Oishi, Riki Ogasawara
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Muscle contraction
Circadian rhythm
Protein synthesis
mTOR
Online Access:https://doi.org/10.1038/s41598-025-06709-z
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