Process optimization and characterization on ultrasonication and microwave-assisted phenolic compounds extraction of Ficus Vasta leaves

Phenolic and flavonoid compounds were extracted from Ficus vasta leaves using ultrasonic and microwave-assisted extraction techniques. For the two chosen extraction techniques, the parameters of the Ficus vasta leaf extraction process was frequency, solute-to-solvent ratio, microwave power, and time...

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Main Authors: Wondifraw Abate Abera, Shimelis Kebede Kassahun, Anteneh Marelign Beyene, Shegaw Ahmed Mohammed
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:Applied Food Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772502225004184
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author Wondifraw Abate Abera
Shimelis Kebede Kassahun
Anteneh Marelign Beyene
Shegaw Ahmed Mohammed
author_facet Wondifraw Abate Abera
Shimelis Kebede Kassahun
Anteneh Marelign Beyene
Shegaw Ahmed Mohammed
author_sort Wondifraw Abate Abera
collection DOAJ
description Phenolic and flavonoid compounds were extracted from Ficus vasta leaves using ultrasonic and microwave-assisted extraction techniques. For the two chosen extraction techniques, the parameters of the Ficus vasta leaf extraction process was frequency, solute-to-solvent ratio, microwave power, and time. In terms of ratio, power, and time, the optimum microwave-assisted extraction process parameters were 0.075 g/mL, 480 watts, and 60 min, respectively. The extract has a maximum total phenol and flavonoid content of 152.5 mg/g and 75.9 mg/g, respectively. However, the extraction procedure assisted by ultrasonication provided a maximum total phenolic content of 214.9 mg/g and a flavonoid content of 87.8 mg/g extract at an optimal solute-to-solvent ratio of 0.075 g/mL, frequency of 50 kHz, and time of 60 min. The functional groups of phenolic compounds, flavonoids, gallic acid, fatty acids, and other significant components were identified by the use of the Fourier infrared spectrum to characterize the leaf extract. The extract contains possible sources of flavonoids, phenolic compounds, and esters, according to the UV-Vis absorbance of light intensity at wavelengths of 254 nm, 283 nm, and 309 nm. The extract's pH was determined to be 4.6 ± 0.8. Using gas chromatography-mass spectroscopy, the elemental components of the raw leaf powder were also examined, yielding crucial details about the extract. 4-pentanal (0.897%), 4-vinyl phenol (1.119%), 2-methylene-N-phenyl methoxy-1cyclopentanone (0.12%), 3,4,5-trihydroxy benzoic acid (0.824%), and limonene (1.26%) were among the phenolic and ester compounds found in the leaf extract. In conclusion, the extraction technique of ultrasonication pretreatment was found to be efficient and faster, with the yield of phenolic and flavonoid significantly influenced by time and power factors.
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spelling doaj-art-42a0db2e02194f7eb8b481274053e8b12025-08-20T03:15:06ZengElsevierApplied Food Research2772-50222025-12-015210111210.1016/j.afres.2025.101112Process optimization and characterization on ultrasonication and microwave-assisted phenolic compounds extraction of Ficus Vasta leavesWondifraw Abate Abera0Shimelis Kebede Kassahun1Anteneh Marelign Beyene2Shegaw Ahmed Mohammed3School of Chemical and Bio Engineering, Addis Ababa Institute of Technology, Addis Ababa University, Addis Ababa, Ethiopia; Department of Chemical Engineering, College of Engineering, Debre Berhan University, Debre Berhan, EthiopiaSchool of Chemical and Bio Engineering, Addis Ababa Institute of Technology, Addis Ababa University, Addis Ababa, Ethiopia; Corresponding author.School of Chemical and Bio Engineering, Addis Ababa Institute of Technology, Addis Ababa University, Addis Ababa, EthiopiaSchool of Chemical and Bio Engineering, Addis Ababa Institute of Technology, Addis Ababa University, Addis Ababa, EthiopiaPhenolic and flavonoid compounds were extracted from Ficus vasta leaves using ultrasonic and microwave-assisted extraction techniques. For the two chosen extraction techniques, the parameters of the Ficus vasta leaf extraction process was frequency, solute-to-solvent ratio, microwave power, and time. In terms of ratio, power, and time, the optimum microwave-assisted extraction process parameters were 0.075 g/mL, 480 watts, and 60 min, respectively. The extract has a maximum total phenol and flavonoid content of 152.5 mg/g and 75.9 mg/g, respectively. However, the extraction procedure assisted by ultrasonication provided a maximum total phenolic content of 214.9 mg/g and a flavonoid content of 87.8 mg/g extract at an optimal solute-to-solvent ratio of 0.075 g/mL, frequency of 50 kHz, and time of 60 min. The functional groups of phenolic compounds, flavonoids, gallic acid, fatty acids, and other significant components were identified by the use of the Fourier infrared spectrum to characterize the leaf extract. The extract contains possible sources of flavonoids, phenolic compounds, and esters, according to the UV-Vis absorbance of light intensity at wavelengths of 254 nm, 283 nm, and 309 nm. The extract's pH was determined to be 4.6 ± 0.8. Using gas chromatography-mass spectroscopy, the elemental components of the raw leaf powder were also examined, yielding crucial details about the extract. 4-pentanal (0.897%), 4-vinyl phenol (1.119%), 2-methylene-N-phenyl methoxy-1cyclopentanone (0.12%), 3,4,5-trihydroxy benzoic acid (0.824%), and limonene (1.26%) were among the phenolic and ester compounds found in the leaf extract. In conclusion, the extraction technique of ultrasonication pretreatment was found to be efficient and faster, with the yield of phenolic and flavonoid significantly influenced by time and power factors.http://www.sciencedirect.com/science/article/pii/S2772502225004184Ficus vastaMicrowave-assisted extractionUltrasonic-assisted extractionPhenolic compoundsFlavonoid compounds
spellingShingle Wondifraw Abate Abera
Shimelis Kebede Kassahun
Anteneh Marelign Beyene
Shegaw Ahmed Mohammed
Process optimization and characterization on ultrasonication and microwave-assisted phenolic compounds extraction of Ficus Vasta leaves
Applied Food Research
Ficus vasta
Microwave-assisted extraction
Ultrasonic-assisted extraction
Phenolic compounds
Flavonoid compounds
title Process optimization and characterization on ultrasonication and microwave-assisted phenolic compounds extraction of Ficus Vasta leaves
title_full Process optimization and characterization on ultrasonication and microwave-assisted phenolic compounds extraction of Ficus Vasta leaves
title_fullStr Process optimization and characterization on ultrasonication and microwave-assisted phenolic compounds extraction of Ficus Vasta leaves
title_full_unstemmed Process optimization and characterization on ultrasonication and microwave-assisted phenolic compounds extraction of Ficus Vasta leaves
title_short Process optimization and characterization on ultrasonication and microwave-assisted phenolic compounds extraction of Ficus Vasta leaves
title_sort process optimization and characterization on ultrasonication and microwave assisted phenolic compounds extraction of ficus vasta leaves
topic Ficus vasta
Microwave-assisted extraction
Ultrasonic-assisted extraction
Phenolic compounds
Flavonoid compounds
url http://www.sciencedirect.com/science/article/pii/S2772502225004184
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