The Bad Reputation of Digoxin in Atrial Fibrillation—Causality or Bias? Nationwide Nested Case-Control Study

The Bad Reputation of Digoxin in Atrial Fibrillation—Causality or Bias? Nationwide Nested Case-Control Study

Aims: Studies have reported excess risk of mortality associated with digoxin in atrial fibrillation (AF).This study sought to investigate if these findings could be replicated and whether a potential association could be explained by bias. Methods: Using Danish Nationwide registers, a nested-case co...

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Bibliographic Details
Main Authors: Anders Holt, Jarl Emanuel Strange, Morten Lock Hansen, Morten Lamberts, Peter Vibe Rasmussen
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:American Journal of Medicine Open
Subjects:
Atrial fibrillation
Digoxin
Negative control outcomes
Pharmacoepidemiology
Residual confounding
Online Access:http://www.sciencedirect.com/science/article/pii/S266703642500007X
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