Negative selection by an endogenous retrovirus promotes a higher-avidity CD4+ T cell response to retroviral infection.
Effective T cell responses can decisively influence the outcome of retroviral infection. However, what constitutes protective T cell responses or determines the ability of the host to mount such responses is incompletely understood. Here we studied the requirements for development and induction of C...
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| Main Authors: | George R Young, Mickaël J-Y Ploquin, Urszula Eksmond, Munisch Wadwa, Jonathan P Stoye, George Kassiotis |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2012-01-01
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| Series: | PLoS Pathogens |
| Online Access: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002709&type=printable |
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