HIV-associated gut dysbiosis drives oncogenesis through metabolic-immune crosstalk: mechanisms and therapeutic implications

HIV-associated gut dysbiosis drives oncogenesis through metabolic-immune crosstalk: mechanisms and therapeutic implications

HIV-induced gut microbiota dysbiosis perpetuates mucosal barrier disruption and systemic inflammation despite antiretroviral therapy (ART), creating a tumor-permissive microenvironment. This review synthesizes evidence linking HIV-associated microbial alterations to oncogenesis through three converg...

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Bibliographic Details
Main Authors: Qingquan Meng, Liran Xu, Furong Xu, Xiaohan Shen, Jingyu Yue
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
Subjects:
HIV
gut microbiota
metabolite
tumor
immune
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1634388/full
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